Human Reproductive and Prenatal Genetics

The second edition of Human Reproductive and Prenatal Genetics provides comprehensive coverage of key topics in human reproductive and prenatal genetics,with a focus on application-driven knowledge. It has been revised to address new and evolving technologies and includes new chapters on chromatin landscapes, sex determination, placental development, metabolism, inflammation, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications.

Format: Hardback
Length: 928 pages
Publication date: 27 March 2023
Publisher: Elsevier Science & Technology

The second edition of Human Reproductive and Prenatal Genetics offers comprehensive coverage of essential topics in human reproductive and prenatal genetics, providing a practical approach to understanding the genetic mechanisms underlying reproductive tract development, gametogenesis, fertilization, implantation, infertility, assisted reproduction, and the placenta. It delves into the genetics and epigenetics of normal and abnormal pregnancies, preimplantation genetic diagnosis and screening, and cutting-edge advancements in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and legal aspects.

The book has been extensively revised to incorporate the latest technologies and advancements in human reproductive genetics. New chapters have been added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in polycystic ovary syndrome (PCOS), pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications.

The text is organized into chapters, each covering a specific topic in detail. The first chapter provides an introduction to human reproductive and prenatal genetics, discussing the importance of understanding genetic factors in reproductive health and the role of genetics in prenatal diagnosis and counseling. The subsequent chapters explore the genetic control of reproductive tract development, gametogenesis, fertilization, implantation, and infertility.

The genetics of female and male infertility are discussed in depth, including the inheritance patterns, genetic mutations, and epigenetic factors that contribute to these conditions. Assisted reproduction techniques, such as in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD), are also explored, with an emphasis on the genetic aspects of these procedures.

The placenta is a crucial organ in pregnancy, and its genetics and epigenetics are extensively examined in the book. The chapter on the placenta covers normal and abnormal pregnancy, preimplantation genetic diagnosis, and screening, as well as the role of the placenta in maternal and fetal health.

In addition to these topics, the book also discusses cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and legal aspects of relevance in the lab and clinic. The use of genetic information in reproductive decision-making, privacy and confidentiality, and the ethical implications of genetic testing are explored in detail.

The second edition of Human Reproductive and Prenatal Genetics is an invaluable resource for researchers, clinicians, and students in the fields of reproductive genetics, obstetrics, and gynecology. It provides a comprehensive and up-to-date overview of the latest research and advancements in the field, making it an essential tool for anyone working in this area.

Weight: 1954g
Dimension: 201 x 248 x 49 (mm)
ISBN-13: 9780323913805
Edition number: 2 ed