Hypoxic Respiratory Failure in the Newborn: From Origins to Clinical Management

Fetal tolerance for intrauterine hypoxia is due to evolutionarily conserved physiological mechanisms, which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This book explores the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies.

Format: Paperback / softback
Length: 254 pages
Publication date: 29 January 2024
Publisher: Taylor & Francis Ltd

Fetal tolerance for intrauterine hypoxia is a remarkable adaptation that arises from evolutionary conserved physiological mechanisms. These mechanisms can be traced back to diving mammals or species living at high altitudes. By understanding fetal hypoxia, we gain insights into the significant physiological changes that occur during the neonatal transition and the dangers associated with perinatal hypoxia.

This comprehensive volume of topical review articles, written by esteemed experts, delves into the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit. It also explores the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate.

The primary objective of "Hypoxic Respiratory Failure in the Newborn" is to bridge the gap between our understanding of hypoxia in extreme environments from animals and how the human fetus manages its hypoxic environment. The book aims to educate healthcare professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies.

Key Features:

Explores the evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, covering basic research to clinical scenarios.

Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care, as well as pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists, in effectively managing infants with hypoxic respiratory failure.

Includes case scenarios that emphasize practical application of the knowledge presented, enhancing the reader's understanding and clinical expertise.

By delving into the complexities of fetal hypoxia and its implications for neonatal health, this book serves as a valuable resource for healthcare professionals seeking to improve outcomes for vulnerable newborns.

Weight: 494g
Dimension: 280 x 210 (mm)
ISBN-13: 9781032078182