Immunology of Endometriosis: Pathogenesis and Management

The book Immunology of Endometriosis: Etiology and Management provides updates on the immunology of endometriosis, including its potential targets for treatment. It emphasizes the role of immune dysregulation in the pathogenesis of the disease.

Format: Paperback / softback
Length: 348 pages
Publication date: 06 December 2021
Publisher: Elsevier Science Publishing Co Inc

Immunology of Endometriosis: Etiology and Management, a volume in the Reproductive Immunology series, offers comprehensive updates on one of the most prevalent gynecological diseases, encompassing fundamental scientific concepts and their clinical implications related to endometriosis immunology. It is widely acknowledged that numerous immunological factors contribute to the development of endometriosis, presenting potential targets for therapeutic interventions.

Endometriosis is recognized as a disease characterized by both endocrine and immune dysregulation. However, the recognition of the direct involvement of two primary physiological mechanisms brings about a significant shift in focus, which holds the potential to advance our understanding of this disease and guide future research endeavors.

The immune system plays a crucial role in the pathogenesis of endometriosis. Studies have revealed that immune cells, including macrophages, lymphocytes, and natural killer cells, infiltrate the endometrial tissue and contribute to the development and progression of the disease. These immune cells are believed to produce inflammatory cytokines and other molecules that promote the growth and survival of endometrial cells, leading to the formation of endometriosis lesions.

Furthermore, recent research has shed light on the role of the immune system in the regulation of endometriosis symptoms. It has been observed that immune cells can influence the production of hormones, such as estrogen and progesterone, which play a key role in the development and progression of endometriosis. Additionally, immune cells can modulate the expression of genes involved in pain perception and inflammation, leading to the development of symptoms such as pelvic pain, dysmenorrhea, and infertility.

In conclusion, the immunology of endometriosis is a rapidly evolving field that holds great promise for the development of new treatments and therapies. By understanding the underlying immunological mechanisms involved in the pathogenesis of endometriosis, researchers can identify potential targets for therapeutic interventions and develop more effective management strategies for patients suffering from this debilitating disease.

Weight: 722g
Dimension: 234 x 191 x 19 (mm)
ISBN-13: 9780128206614