Innovative Treatment Strategies for Clinical Electrophysiology

This book provides an overview of advancements in clinical electrophysiology, focusing on ablation and pacing, devices and signal processing, and selected strategies such as in situ cell reprogramming, artificial intelligence, and cardiac digital twinning. It aims to give the reader a good background of established practices and present novel approaches for rhythm restoration and control.

Format: Hardback
Length: 134 pages
Publication date: 07 December 2022
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the forefront of clinical electrophysiology, providing a thorough understanding of the field's advancements. It serves as a valuable resource for both professionals and students, offering a solid foundation in established practices. To effectively address such a broad subject matter, the book focuses on two central aspects: ablation and pacing. In-depth discussions are presented on novel energy sources and innovative approaches to rhythm restoration and control, while also exploring the latest devices and signal processing techniques that aid in clinical practice and home medicine. Additionally, the book presents the reader with select strategies that are poised to revolutionize the field, including in situ cell reprogramming, harnessing the recent breakthroughs in epigenetic modification of somatic cells, the application of artificial intelligence, and cardiac digital twinning, which aims to consolidate information from imaging, mechanics, and electrophysiology to create personalized treatment models for patients.

Clinical Electrophysiology: Advances and Paradigm Shifts

Clinical electrophysiology has witnessed remarkable advancements in recent years, driven by technological innovations and scientific discoveries. This book serves as a comprehensive guide to the field, highlighting the latest developments in various sub-specialties.

In the first chapter, the authors provide an overview of the fundamentals of clinical electrophysiology, including the anatomy and physiology of the heart, the conduction system, and the mechanisms of arrhythmias. This foundational knowledge is essential for understanding the subsequent chapters, which delve into the latest techniques and therapies.

The second chapter focuses on ablation, a technique used to treat arrhythmias by targeting specific cardiac structures. The authors discuss the various ablation modalities, such as radiofrequency ablation (RFA), cryoablation, and thermal ablation, and their applications in treating various arrhythmias, including atrial fibrillation, ventricular tachycardia, and supraventricular tachycardia. They also explore the emerging technologies, such as magnetic resonance imaging-guided ablation and real-time mapping systems, that are enhancing the precision and safety of ablation procedures.

The third chapter explores pacing, another essential aspect of clinical electrophysiology. The authors discuss the different types of pacemakers, including single-chamber pacemakers, dual-chamber pacemakers, and cardiac resynchronization therapy (CRT) devices. They also explore the indications for pacing, the advantages and disadvantages of different pacing strategies, and the emerging technologies, such as leadless pacemakers and remote monitoring systems, that are improving patient outcomes.

In the fourth chapter, the authors discuss the role of devices and signal processing in clinical electrophysiology. They discuss the various electrophysiology monitoring devices, such as electrocardiograms (ECGs), event recorders, and intracardiac echocardiograms, and their applications in diagnosing and treating arrhythmias. They also explore the emerging technologies, such as artificial intelligence and machine learning, that are being used to analyze large datasets and improve the accuracy of arrhythmia detection and diagnosis.

The fifth chapter focuses on in situ cell reprogramming, a promising technique for treating heart diseases. The authors discuss the mechanisms of cell reprogramming, the potential applications of this technique in heart disease treatment, and the challenges and limitations associated with this approach. They also explore the emerging technologies, such as stem cell therapy and gene editing, that are being used in conjunction with in situ cell reprogramming to enhance its effectiveness.

The sixth chapter discusses the use of artificial intelligence in clinical electrophysiology. The authors discuss the various applications of artificial intelligence, such as machine learning algorithms for arrhythmia detection, decision-making support systems for pacemaker implantation, and virtual reality simulations for patient education and training. They also explore the ethical and regulatory considerations associated with the use of artificial intelligence in healthcare.

The seventh chapter focuses on cardiac digital twinning, a novel approach for personalized treatment of heart diseases. The authors discuss the concept of cardiac digital twinning, the technologies used to create virtual models of the heart, and the applications of cardiac digital twinning in predicting disease progression, designing personalized treatment plans, and monitoring patient outcomes. They also explore the challenges and limitations associated with cardiac digital twinning and the potential for this approach to revolutionize the field of clinical electrophysiology.

In conclusion, this book provides a comprehensive and up-to-date overview of clinical electrophysiology, covering a wide range of topics. It is an essential resource for professionals, students, and researchers in the field, offering valuable insights into the latest advancements and emerging strategies. As the field continues to evolve, this book will remain a valuable reference for years to come.

Weight: 383g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811966484
Edition number: 1st ed. 2022