Shulph Ink

Intestine

Intestine

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  • More about Intestine

The intestine is a leading organ for stem cell biology and function research, with advanced in vitro and in vivo tools and approaches used to investigate stem cell potential in treating intestinal diseases. This volume discusses cutting-edge research using human and murine organoid cultures, genetic editing, iPS cell models, haploid cells, genetically engineered mice, and stem cell transplantation to cure diseases.

Format: Paperback / softback
Length: 204 pages
Publication date: 18 June 2021
Publisher: Elsevier Science Publishing Co Inc


The intestine holds a prominent position among the leading organs, and in recent years, a multitude of cutting-edge in vitro and in vivo research tools and approaches have been developed and utilized to delve into the realm of stem cell biology and function. These innovative methodologies encompass human and murine organoid cultures, genetic editing techniques both in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic and compound screening paradigms, genetically engineered mice, and stem cell transplantation for the treatment of various diseases.

Stem Cell Innovation in Health and Disease: Volume 1: The Intestine presents two comprehensive sections that highlight groundbreaking research aimed at unraveling the intricacies of stem cell functions within the intestine and developing effective strategies to translate stem cells from the laboratory to the clinical setting. Within these sections, readers will find insights spanning from the utilization of mouse and human organoid cultures, genetic editing methodologies in vitro and in vivo, and human iPS cell models to study stem cell functions and simulate intestinal diseases. Furthermore, the cutting-edge research encompasses the potential application of iPSCs, ESCs, and blood stem cells (stem cell transplants) in the treatment of intestinal diseases and disorders.

This volume serves as a testament to the fact-based promise of stem cells and regenerative medicine in the intestine, shedding light on the potential for these therapies to revolutionize the field of gastrointestinal health. By exploring the latest advancements in stem cell research, this book provides a valuable resource for researchers, clinicians, and healthcare professionals seeking to advance our understanding of intestinal biology and develop innovative treatments for intestinal disorders.

Weight: 436g
Dimension: 188 x 234 x 17 (mm)
ISBN-13: 9780128212691

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