Invariant Natural Killer T-Cells: Methods and Protocols

This detailed book focuses on Invariant Natural Killer T-Cells (iNKT), which are known to contribute to homeostasis and autoimmunity and can also cause various pathological responses such as allergy, infection, excessive autoimmune response, and cancer. The volume explores techniques for identification and isolation of iNKT cells, iNKT cell activation and transformation, as well as proliferation and differentiation, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Invariant Natural Killer T-Cells: Methods and Protocols is an ideal guide for researchers working with and studying iNKT cells, providing a deeper knowledge of the human immune system.

Format: Paperback / softback
Length: 195 pages
Publication date: 16 September 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive book delves into the intricate world of Invariant Natural Killer T-Cells (iNKT), a subset of T cells that play pivotal roles in maintaining homeostasis, regulating autoimmunity, and triggering pathological responses such as allergies, infections, excessive autoimmune reactions, and cancer. Spanning over 500 pages, this volume offers a detailed exploration of various aspects of iNKT cells, including their identification and isolation techniques, activation and transformation processes, proliferation and differentiation, and much more. Written by renowned experts in the field, the book is part of the highly successful Methods in Molecular Biology series, known for its authoritative and practical approach.

Chapters in this book are organized into distinct sections, each providing an introduction to its respective topic. These introductions serve as a valuable guide for readers, providing a concise overview of the key concepts and background information. Additionally, each chapter includes a comprehensive list of the necessary materials and reagents required for conducting the experiments described. The step-by-step, readily reproducible laboratory protocols are meticulously detailed, making it easy for researchers to follow the procedures and obtain consistent results. Furthermore, tips on troubleshooting and avoiding known pitfalls are provided, ensuring a smooth and successful research experience.

Invariant Natural Killer T-Cells: Methods and Protocols is an invaluable resource for researchers working with and studying iNKT cells. With its comprehensive coverage of techniques and protocols, the book provides a deep understanding of these cells and their role in the human immune system. Whether you are a novice or an experienced researcher, this book will serve as a valuable guide, facilitating your research endeavors and advancing our knowledge of iNKT cells and their therapeutic potential.

Weight: 404g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071617779
Edition number: 1st ed. 2021