Long Term Safety of Assisted Reproduction

Assisted reproductive technologies are generally safe for babies and mothers, but long-term outcomes are still scarce. More research is needed to cover the lack of data in specific patient groups and recently developed treatments.

Format: Hardback
Length: 212 pages
Publication date: 28 March 2022
Publisher: Taylor & Francis Ltd

A comprehensive examination of the growing body of evidence suggests that assisted reproductive technologies (ARTs) are generally safe for both infants and mothers. Nevertheless, the literature is rife with reports of increased risks of obstetric and perinatal complications. Regarding long-term outcomes for women and children, the data remains limited. The chapters presented in this book review provide an up-to-date overview of the current understanding of the long-term safety of assisted reproduction and emphasize the need for ongoing research to address gaps in data for specific patient populations and recently developed treatments with limited follow-up periods.

ARTs encompass a range of techniques used to assist in conception, including in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and surrogacy. While these technologies have been widely used and have led to many successful pregnancies, there are concerns about their long-term effects on both the baby and the mother. One of the primary concerns is the risk of birth defects. Studies have shown that ARTs may increase the risk of certain birth defects, such as Down syndrome, cleft lip and palate, and neural tube defects. However, it is important to note that the overall risk of birth defects is still relatively low, and many couples who undergo ARTs have healthy babies.

Another concern is the risk of pregnancy complications. Women who undergo ARTs may be at higher risk of developing conditions such as gestational diabetes, preeclampsia, and preterm birth. These complications can be serious and may have long-term effects on both the mother and the baby. However, it is worth noting that many women who undergo ARTs are also at higher risk of these conditions due to factors such as age, obesity, and underlying medical conditions.

In terms of long-term outcomes for women and children, there is still limited data available. Studies have shown that women who undergo ARTs may have an increased risk of certain health conditions, such as breast cancer and ovarian cancer. However, it is important to note that these risks are still relatively low and that the benefits of ARTs often outweigh the risks.

Children born through ARTs may also face unique challenges. For example, children born through surrogacy may have questions about their biological parents and may experience feelings of abandonment or rejection. Additionally, children born through ARTs may be at higher risk of developing certain genetic disorders, such as mitochondrial disorders, due to the manipulation of genetic material during the treatment process.

Despite these concerns, it is important to note that assisted reproductive technologies are still considered safe for most couples. The risks associated with ARTs are generally low, and the benefits of successful pregnancies can be significant. However, it is important for couples to carefully consider the risks and benefits of ARTs and to work closely with their healthcare providers to ensure that they are making informed decisions about their reproductive health.

In conclusion, assisted reproductive technologies are generally safe for both babies and mothers. However, there are concerns about the risk of birth defects, pregnancy complications, and long-term outcomes for women and children. Ongoing research is needed to better understand the long-term safety of ARTs and to address any gaps in data for specific patient populations. Couples who are considering ARTs should work closely with their healthcare providers to ensure that they are making informed decisions about their reproductive health.

Dimension: 254 x 178 (mm)
ISBN-13: 9780367511234