Management of Peritoneal Metastases- Cytoreductive Surgery, HIPEC and Beyond

The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients.

Format: Hardback
Length: 580 pages
Publication date: 13 April 2018
Publisher: Springer Verlag, Singapore

The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject.

This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to provide evidence-based answers to address them. All chapters were written and/or reviewed by leading experts in this field.

Peritoneal metastases are a significant challenge for patients with cancer, and there is a growing need for effective treatments. Cytoreductive surgery and HIPEC have emerged as promising approaches, but there is still much to be learned about their optimal use and potential side effects. This book aims to provide a comprehensive overview of the current state of knowledge in this field, with a focus on practical issues that surgical oncologists encounter in their daily practice.

Chapter 1 provides an introduction to peritoneal metastases and their management. The authors discuss the prevalence of peritoneal metastases, the different types of cancer that can cause them, and the factors that contribute to their development. They also provide an overview of the current treatment options, including cytoreductive surgery and HIPEC.

Chapter 2 focuses on the surgical aspects of managing peritoneal metastases. The authors discuss the different surgical techniques used, such as laparoscopic surgery, open surgery, and robotic surgery, and their advantages and disadvantages. They also provide an overview of the surgical staging process, which is essential for determining the appropriate treatment plan.

Chapter 3 discusses the role of chemotherapy in the management of peritoneal metastases. The authors review the different chemotherapy regimens used, including systemic chemotherapy, intraperitoneal chemotherapy, and targeted therapy, and their effectiveness in treating peritoneal metastases. They also discuss the potential side effects of chemotherapy and the strategies used to manage them.

Chapter 4 explores the role of radiation therapy in the management of peritoneal metastases. The authors discuss the different radiation therapy techniques used, such as external beam radiation therapy, brachytherapy, and stereotactic body radiation therapy, and their advantages and disadvantages. They also provide an overview of the radiation dosing and treatment planning process, which is critical for achieving optimal outcomes.

Chapter 5 discusses the role of immunotherapy in the management of peritoneal metastases. The authors review the different immunotherapy agents used, such as checkpoint inhibitors, immune checkpoint modulators, and adoptive cell therapy, and their effectiveness in treating peritoneal metastases. They also discuss the potential side effects of immunotherapy and the strategies used to manage them.

Chapter 6 discusses the role of targeted therapy in the management of peritoneal metastases. The authors discuss the different targeted therapy agents used, such as tyrosine kinase inhibitors, monoclonal antibodies, and small molecule drugs, and their effectiveness in treating peritoneal metastases. They also discuss the potential side effects of targeted therapy and the strategies used to manage them.

Chapter 7 discusses the role of surgery in the management of peritoneal metastases. The authors discuss the different surgical techniques used in peritoneal metastases, such as debulking surgery, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy (HIPEC). They also provide an overview of the surgical staging process, which is essential for determining the appropriate treatment plan.

Chapter 8 discusses the role of perioperative care in the management of peritoneal metastases. The authors discuss the different perioperative care strategies used, such as preoperative optimization, intraoperative management, and postoperative care, and their impact on patient outcomes. They also provide an overview of the potential complications associated with peritoneal metastases and the strategies used to manage them.

Chapter 9 discusses the role of palliative care in the management of peritoneal metastases. The authors discuss the different palliative care strategies used, such as pain management, symptom control, and psychosocial support, and their impact on patient quality of life. They also provide an overview of the resources available to patients and their families, such as support groups and counseling services.

Chapter 10 discusses the future directions in the management of peritoneal metastases. The authors discuss the emerging therapies and technologies that are being developed to improve the treatment of peritoneal metastases, such as precision medicine, immunotherapy, and targeted therapy. They also discuss the challenges that remain in the management of peritoneal metastases, such as the lack of effective biomarkers and the need for better patient education and support.

In conclusion, this book provides a comprehensive and up-to-date overview of the management of peritoneal metastases. It is an essential resource for surgical oncologists, oncologists, and other healthcare professionals who are involved in the care of patients with peritoneal metastases. The authors have brought together leading experts in this field to provide evidence-based answers to the most pressing questions in this area, and the book is sure to be a valuable tool for practitioners and researchers alike.

Weight: 1496g
Dimension: 185 x 262 x 37 (mm)
ISBN-13: 9789811070525
Edition number: 1st ed. 2018