Management of the Breast and Axilla in the Neoadjuvant Setting

Breast cancer management has made great strides in improving oncologic treatment outcomes, particularly in patients with early-stage disease. This multidisciplinary collaboration between breast imagers, surgeons, medical oncologists, and radiation oncologists has led to individualized treatment strategies with a great emphasis on the intrinsic disease biology. Neoadjuvant systemic therapy has broadened the indications for breast surgery, presenting new challenges and opportunities to scale down on the extent of local therapy and its toxicity. This book will provide a comprehensive, state-of-the-art review of this field, including novel and evolving strategies in neoadjuvant systemic therapy, appropriate axillary imaging, innovative surgical techniques, and Radiation Oncology concepts. It will serve as a valuable resource for clinicians and researchers with an interest in breast cancer.

Format: Paperback / softback
Length: 377 pages
Publication date: 16 December 2022
Publisher: Springer Nature Switzerland AG

Over the past few decades, breast cancer management has made remarkable strides in improving oncologic treatment outcomes, particularly in patients with early-stage disease. While widespread access to screening, leading to early detection, is undoubtedly responsible for this trend, the management of breast cancer has evolved into a complex multidisciplinary collaboration between breast imagers, surgeons, medical oncologists, and radiation oncologists. As a result, with a better understanding of multidisplinary goals and challenges, treatment strategies have become more individualized, with a significant emphasis on the intrinsic disease biology. Furthermore, the indications for neoadjuvant systemic therapy have significantly broadened, allowing a substantial number of patients with early-stage breast cancer to benefit from this strategy to reduce the extent of breast surgery they would undergo at its completion. As such, the management of the axilla in these patients has presented with new challenges as well as new opportunities to scale down on the extent of local therapy and, consequently, its toxicity.

This text will provide a comprehensive, state-of-the-art review of this field, serving as a valuable resource for clinicians (surgeons, medical oncologists, radiation oncologists) and researchers with an interest in breast cancer. The book will review novel and evolving strategies in neoadjuvant systemic therapy for early-stage breast cancer, provide new perspectives about appropriate axillary imaging in anticipation of neoadjuvant systemic therapy, and describe new data on innovative surgical techniques and Radiation Oncology concepts designed to deescalate the extent and toxicity of local therapy.

In conclusion, the management of breast cancer has undergone a remarkable transformation over the past few decades, driven by advancements in screening, multidisciplinary collaboration, and individualized treatment strategies. With better understanding of the disease biology and expanded indications for neoadjuvant systemic therapy, clinicians and researchers are poised to make further progress in improving outcomes for patients with breast cancer.

Weight: 599g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030880224
Edition number: 1st ed. 2022