Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms is a comprehensive introduction to state-of-the-art micro and nano systems developed for biophysical studies of cells and small organisms. These systems range from MEMS and microfluidic devices to robotic micro-nanomanipulation systems and cover topics from cell mechanics to neural science.

Format: Paperback / softback
Length: 404 pages
Publication date: 17 August 2021
Publisher: Elsevier Science Publishing Co Inc

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms is a comprehensive guide to the cutting-edge micro and nano systems that have recently been developed and applied to the study of cells and small organisms. These systems encompass a wide range of technologies, including microelectromechanical systems (MEMS) and microfluidic devices, as well as robotic micro-nanomanipulation systems. The scope of biophysical studies conducted using these systems is vast, ranging from cell mechanics to the neural science of worms and Drosophila. This book aims to provide readers with a solid understanding of the fundamentals involved in the development of these tools and to showcase the latest advancements in cellular and organismal biophysics enabled by these technologies.

MEMS, or microelectromechanical systems, are microscopic devices that combine electrical and mechanical components. They have numerous applications in biomedicine, such as drug delivery systems, biosensors, and tissue engineering. MEMS devices can be designed to be extremely small, with features measured in micrometers or nanometers, allowing for precise control and manipulation of biological processes.

Microfluidic devices are another important class of micro and nano systems used in biophysical studies. These devices are designed to manipulate small volumes of fluids, typically in the range of nanoliters or picoliters. They are used for a variety of purposes, including cell culture, drug discovery, and genetic analysis. Microfluidic devices allow for the precise control of environmental conditions, such as temperature, pH, and flow rates, which can have a significant impact on the behavior of cells and small organisms.

Robotic micro-nanomanipulation systems are a newer class of micro and nano systems that have emerged in recent years. These systems are designed to perform precise manipulations on cells and small organisms at the nanoscale level. They can be used for a variety of purposes, such as drug delivery, tissue engineering, and genetic manipulation. Robotic micro-nanomanipulation systems allow for high-throughput experimentation and the ability to study complex biological processes in real time.

One of the key applications of micro and nano systems in biophysical studies is the study of cell mechanics. Cell mechanics is the study of how cells respond to mechanical forces, such as those imposed by the extracellular matrix or by other cells. By using micro and nano systems, researchers can study the mechanical properties of cells, such as their stiffness, elasticity, and viscoelasticity, and how these properties change in response to different environmental conditions.

Another important area of biophysical studies using micro and nano systems is the study of neural science. Neural science is the study of the nervous system, including the brain, spinal cord, and peripheral nerves. By using micro and nano systems, researchers can study the structure and function of neurons, as well as the interactions between neurons and other cells in the nervous system. This can help us better understand the mechanisms of learning, memory, and behavior.

In addition to these applications, micro and nano systems are also used in biophysical studies of other small organisms, such as worms and Drosophila. These organisms are important model systems for studying biological processes, such as development, metabolism, and disease. By using micro and nano systems, researchers can study the behavior of these organisms at the cellular and molecular level, and gain insights into the underlying mechanisms of these processes.

Overall, micro and nano systems for biophysical studies of cells and small organisms have revolutionized our understanding of biological processes. These systems have enabled us to study cells and small organisms in unprecedented detail, and have opened up new avenues for drug discovery, tissue engineering, and genetic manipulation. As these technologies continue to evolve, we can expect to see even more exciting developments in the field of biophysics.

Weight: 860g
Dimension: 235 x 191 (mm)
ISBN-13: 9780128239902