Microbial Genomic Islands in Adaptation and Pathogenicity

This book explores the role of microbial genomic islands (GEIs) in genome stability, plasticity, evolutionary adaptation, and pathogenicity in the bacterial population. It provides tools and techniques for analyzing GEIs and discusses their importance in bacterial speciation, gene acquisition, and adaptation. It also highlights recent advances in understanding their distribution, evolution, and mechanistic modes of behavior in pathogenic, non-pathogenic, and environmental species.

Format: Hardback
Length: 356 pages
Publication date: 01 April 2023
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the intricate realm of microbial genomic islands (GEIs), exploring their pivotal role in genome stability, plasticity, evolutionary adaptation, and pathogenicity within the bacterial population. The initial chapters provide a comprehensive introduction to the various tools and techniques employed for the analysis of these genomic regions, including bioinformatics, artificial intelligence, machine learning, next-generation sequencing, and molecular biology methodologies. The book further emphasizes the significance of genomic islands in bacterial speciation, the acquisition of genes associated with resistome, nitrogen fixation, mobilomes, and nutritional fitness, as well as their contribution to adaptation. By presenting recent advancements in our understanding of microbial genomic islands distribution, evolution, and mechanistic modes of behavior across pathogenic, non-pathogenic, and environmental species, this book serves as a valuable resource for beginners in molecular microbiology, students, researchers, clinicians, stakeholders, and policymakers seeking to unravel the complexities of GEIs in the adaptive evolution of microorganisms.

Weight: 735g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811993411
Edition number: 1st ed. 2023