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MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine

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  • More about MicroRNA in Regenerative Medicine

The genomes 2,654 newly discovered variants of mature microRNAs hold a key role in the body's toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies.

Format: Hardback
Length: 1104 pages
Publication date: 01 September 2022
Publisher: Elsevier Science Publishing Co Inc


The genomes of 2,654 newly discovered variants of mature microRNAs, short ribonucleic acid molecules found in eukaryotic cells, play a crucial role in the body's toolkit of regenerative and reparative capacities. By identifying how to activate and deliver these specialist molecules, researchers hope to aid in the repair and regeneration of major tissue and organ damage in future therapies.

In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNAs in cell and tissue plasticity, developmental biology, tissue repair, and regeneration.

In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet-derived microRNAs in tissue development, ocular microRNAs, mitochondrial microRNAs, sensory hair cell death and regeneration, and microRNAs in senescence.

The discovery of these novel microRNAs has opened up new avenues for research and therapeutic development in regenerative medicine. By understanding the role of miRNAs in tissue repair and regeneration, researchers can develop targeted interventions to promote healing and restore function to damaged tissues. This field holds great promise for improving the quality of life for individuals with chronic diseases and injuries.


Dimension: 276 x 216 (mm)
ISBN-13: 9780128207192
Edition number: 2 ed

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