Molecular Basis of Oxidative Stress: Chemistry, To xicology, Disease Pathogenesis, Diagnosis, and The rapeutics, 2nd Edition

Molecular Basis of Oxidative Stress is a comprehensive resource on the molecular and chemical bases of oxidative stress, providing insight on various diseases caused by oxidative stress and the role of reactive oxygen species in disease pathogenesis. It includes new chapters on oxidative stress mechanisms, biomarkers, and therapeutic strategies and covers developments in the field in the last several years.

Format: Hardback
Length: 650 pages
Publication date: 02 May 2023
Publisher: John Wiley and Sons Ltd

Oxidative stress is a condition in which there is an excess of reactive oxygen species (ROS) in the body, which can damage cells and tissues. The molecular and chemical bases of oxidative stress are complex and multifaceted, and understanding these mechanisms is essential for developing effective treatments for diseases caused by oxidative stress.

Molecular Basis of Oxidative Stress is a comprehensive resource that provides in-depth knowledge on the molecular and chemical bases of oxidative stress. It covers various diseases caused by oxidative stress, such as cancer, cardiovascular disease, and neurodegenerative diseases. The book also discusses the role of reactive oxygen species (ROS) in disease pathogenesis and the mechanisms of oxidative stress and damage.

The Second Edition of Molecular Basis of Oxidative Stress has been thoroughly updated and expanded to reflect advances in the field since its original publication. It includes new chapters on oxidative stress mechanisms, biomarkers, and therapeutic strategies for managing and treating diseases. The book also covers emerging diseases, such as kidney and eye diseases and COPD.

Written by a team of highly qualified academics, Molecular Basis of Oxidative Stress discusses various topics related to oxidative stress, including classification, physico-chemical properties, sources, and detection of reactive species. It also explores the etiology of COPD from cigarette smoke and pollution and the oxidative, reductive, and indirect non-redox modifications of key biomolecular systems such as lipids, proteins, and DNA by reactive species.

The book also discusses gene expression of antioxidant defense enzymes, mitochondrial dysfunction, and aberrant activation of NOX and cell signaling. Biomarkers of oxidative stress in neurodegenerative diseases are also covered in detail.

Overall, Molecular Basis of Oxidative Stress is a valuable resource for researchers, physicians, and students interested in oxidative stress and its implications for disease. It provides comprehensive coverage of the molecular and chemical bases of oxidative stress, as well as its role in disease pathogenesis and therapeutics.

Weight: 666g
ISBN-13: 9781119790266