Motor Neurone Disease

The International Review in Neurobiology serial, Motor Neurone Disease, Volume 176, highlights new advances in the field, including clinical features, genetics, neurophysiology, symptom management, and biomarkers. It also covers mitochondrial dysfunction, neuroprotective therapies, glial cells, RNA biology, and pre-clinical models.

Format: Hardback
Length: 322 pages
Publication date: 01 May 2024
Publisher: Elsevier Science Publishing Co Inc

The 176th volume of the International Review in Neurobiology, titled "Motor Neurone Disease," showcases groundbreaking advancements in the field. This latest edition presents captivating chapters authored by an esteemed international panel of experts. The updates encompass a wide range of topics, including Clinical features, differential diagnosis, and pathology, Recent advances in genetics of familial and sporadic ALS, Non-coding genome contribution to ALS, Contribution of neurophysiology to the diagnosis and monitoring of ALS, Advances in symptom management and monitoring disease progression, Use of biomarkers in clinical trials, and future developments aimed at identifying new biomarkers.

Furthermore, the book delves into the application of systems biology to identify therapeutic targets, as well as exploring other crucial aspects such as Evidence of mitochondrial dysfunction (in ALS) and how to measure it in model systems, Current neuroprotective therapies and future prospects, The role of glial cells in ALS, Dysregulation of RNA biology in ALS, and New developments in pre-clinical models of ALS to guide translation.

This comprehensive resource provides valuable insights into the latest developments in motor neurone disease research, offering a valuable reference for researchers, clinicians, and healthcare professionals alike.

Dimension: 229 x 151 (mm)
ISBN-13: 9780443141164