Multiple Sequence Alignments: Which Program Fits My Data?

This book provides a comprehensive overview of multiple sequence alignments (MSAs) and offers practical guidance for biologists who use them in their data analysis. It addresses uncertainty among researchers about how MSA programs work and helps them choose the right program for their data. The first part explains the possible fields of application and the formats produced by MSA programs, while the second part compares different MSA programs based on data.

Format: Paperback / softback
Length: 103 pages
Publication date: 19 February 2022
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

This book is a comprehensive guide for biologists who utilize multiple sequence alignments (MSAs) in their data analysis, seeking a thorough understanding of the diverse range of programs available. Despite the crucial significance of MSAs in data analysis, researchers often face uncertainty regarding the precise workings of these programs, as well as the factors that influence the different outcomes of various analyses. This book aims to address these concerns by providing helpful explanations and background information, without requiring extensive bioinformatics expertise. It gradually introduces the reader to the topic, making it accessible to a wide audience.

In the first part of the book, the potential applications and the commonly produced formats by MSA programs are extensively described. The central algorithms and the internal mechanisms of the most widely used MSA programs from both the past and the present are explained in a straightforward and detailed manner. This section aims to provide a solid foundation for the reader, enabling them to grasp the fundamental concepts and principles of MSA analysis.

The second part of the book is a comprehensive data-based comparison between various MSA programs. This comparison is designed to assist the reader in making an informed decision about which program to use for their next alignment. Each program is evaluated based on its features, functionalities, and performance, with an emphasis on its suitability for different types of data and analysis objectives. The book includes detailed examples and case studies to illustrate the practical applications of the different programs, helping the reader to apply the knowledge gained in a real-world setting.

By offering a comprehensive and detailed overview of MSA programs, this book serves as a valuable resource for biologists who require a deeper understanding of these tools in their data analysis. It addresses the uncertainty surrounding the workings of these programs and provides practical guidance for selecting the most appropriate program for specific research needs. Whether you are a novice or an experienced biologist, this book will help you leverage the power of MSAs to uncover valuable insights and make informed decisions based on your data.

Weight: 191g
Dimension: 235 x 155 (mm)
ISBN-13: 9783662644720
Edition number: 1st ed. 2022