Nanomaterials for Photodynamic Therapy

Nanomaterials for Photodynamic Therapy focuses on the use of nanomaterials and nanocarriers for photodynamic therapy, discussing existing and emerging materials, challenges, and translational aspects. It is useful for researchers in cancer treatment.

Format: Paperback / softback
Length: 568 pages
Publication date: 01 January 2023
Publisher: Elsevier Science Publishing Co Inc

Nanomaterials for Photodynamic Therapy (PDT) presents a novel approach to this field, emphasizing the utilization of nanomaterials and nanocarriers for photodynamic therapy (PDT). The book delves into the historical background and underlying mechanism of PDT, encompassing the diverse range of sensitizers currently available. Subsequent chapters explore existing and emerging nanomaterials for PDT, encompassing hydrogel nanocomposites, fullerenes, quantum dots, polymeric micelles, and more. Additionally, challenges and translational aspects of PDT are addressed, shedding light on the issues and barriers associated with drug-resistant cancers. This book serves as a bridge between the physics and clinical realms of PDT, offering a distinctive nanomaterials-centric perspective. It is an invaluable resource for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists engaged in cancer treatment.

Introduction:
Nanomaterials for Photodynamic Therapy (PDT) offers a unique perspective on this field, focusing on the use of nanomaterials and nanocarriers for photodynamic therapy (PDT). The book provides an in-depth exploration of the historical background and underlying mechanism of PDT, encompassing the diverse range of sensitizers currently available.

Chapter 1: Historical Background and Mechanism of Action:
In this chapter, the book delves into the origins and development of PDT, shedding light on the pioneering work of scientists who laid the foundation for this therapeutic approach. It also discusses the fundamental principles behind PDT, including the interaction of light with sensitizers and the subsequent generation of reactive oxygen species (ROS) that are responsible for the destruction of cancer cells.

Chapter 2: Variety of Sensitizers:
The book introduces the various sensitizers used in PDT, including natural compounds, synthetic dyes, and metal complexes. Each sensitizer is discussed in detail, including its chemical structure, photophysical properties, and potential applications in cancer treatment.

Chapter 3: Existing and Emerging Nanomaterials for PDT:
In this chapter, the book explores the existing and emerging nanomaterials for PDT, including hydrogel nanocomposites, fullerenes, quantum dots, polymeric micelles, and other advanced materials. Each nanomaterial is evaluated in terms of its physicochemical properties, photodynamic properties, and potential applications in cancer therapy.

Chapter 4: Challenges and Translational Aspects of PDT:
The book addresses the challenges and translational aspects of PDT, emphasizing the need for effective sensitizer delivery, optimization of light sources, and development of targeted nanocarriers. It also discusses the potential limitations of PDT, such as drug resistance and side effects, and explores strategies to overcome these obstacles.

Conclusion:
Nanomaterials for Photodynamic Therapy provides a comprehensive and up-to-date overview of the field, covering the history, mechanism of action, variety of sensitizers, existing and emerging nanomaterials, challenges, and translational aspects of PDT. It is an invaluable resource for materials scientists, biomedical engineers, electrical and optical engineers, and pharmaceutical scientists interested in cancer treatment.

Weight: 1000g
Dimension: 229 x 152 (mm)
ISBN-13: 9780323855952