Nanotechnology Tools for Infections Control explores the development of nanotechnology platforms for pathogen eradication and drug resistance, focusing on biocompatible and biodegradable nanosystems with responsive nanoparticles. It introduces nanobots that can self-propel in response to external stimuli and discusses their applications as alternative antibiotics, including pharmokinetic and dynamics, biological barrier crossing, and intracellular trafficking. The immune system and protein corona's role in nanoparticle retention are also highlighted.

Format: Paperback / softback
Length: 412 pages
Publication date: 01 September 2024
Publisher: Elsevier Science Publishing Co Inc

Nanotechnology Tools for Infections Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance offers a comprehensive exploration of recent advancements in nanotechnology platforms, with a particular emphasis on the development of biocompatible and biodegradable nanosystems. The book delves into the rationale behind the design of raw materials, synthetic procedures, and characterization techniques, and introduces a novel generation of nanomaterials known as "nanobots" that possess the ability to self-propel in response to external stimuli. Subsequent sections of the book delve into the applications of nanosystems as an alternative approach to standard antibiotics, covering their pharmacokinetics and dynamics within the body, their ability to cross biological barriers, and their distribution within different body compartments. A dedicated section highlights the crucial role of the immune system and protein corona in altering the retention of nanoparticles within the body. Additionally, the book provides coverage of how nanosystems access different cells and their intracellular trafficking.

Nanotechnology Tools for Infections Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance

Nanotechnology Tools for Infections Control: Scanning New Horizons on Next-Generation Therapies to Eradicate Pathogens and Fight Drug Resistance provides an overview of recent strategies to build nanotechnology platforms, with a specific focus on biocompatible and biodegradable nanosystems. Particular attention is given to responsive nanoparticles, which are able to sense and respond to specific external stimuli (e.g., temperature, pH). The book includes details of the rationale behind the design of the raw materials, synthetic procedures and characterization techniques. It also introduces a new generation of nanomaterials, commonly named as 'nanobots', which are able to self-propel in response to external stimuli. Subsequent sections of the book focus on the applications of nanosystems as an alternative approach to standard antibiotics. The chapters describe their pharmacokinetics and dynamics within the body, their ability to cross biological barriers and how they distribute within different body compartments. In this respect, a dedicated section highlights the crucial role of the immune system, as well as of protein corona, in changing the nanoparticles retention within the body. Coverage is also given to describe how nanosystems access different cells and their intracellular trafficking.

Dimension: 235 x 191 (mm)
ISBN-13: 9780128239940