Natural Product Experiments in Drug Discovery

This book explores a wide range of evidence-based complementary medicine and bio-analytical techniques used to define botanical products. It includes unique contributions on phytomedicine and screening biological activities, as well as issues related to herbal medications, and serves as an ideal reference for students, professors, and researchers.

Format: Hardback
Length: 561 pages
Publication date: 21 September 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into a diverse array of evidence-based complementary medicine and various bio-analytical techniques employed to characterize botanical products. Compiling recent research and emerging advancements in the field of contemporary phytomedicine, along with their potential applications in human health care, the book features unique contributions in the form of chapters on phytomedicine and screening biological activities elucidated through diverse hyphenated techniques, as well as issues pertaining to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Authored for the Springer Protocols Handbooks series, chapters offer guidance from esteemed experts on optimal approaches for conducting future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an invaluable reference for students, professors, and researchers in universities, R&D institutions, pharmaceutical and herbal enterprises, and health organizations.

Introduction:
The utilization of natural products in drug discovery has gained significant attention in recent years due to their rich diversity and potential therapeutic benefits. Botanical products, derived from plants, have been used for centuries in traditional medicine and continue to be explored for their medicinal properties. In this comprehensive volume, we aim to provide a detailed exploration of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products.

Chapter 1:
In the first chapter, we provide an overview of the field of complementary medicine, including its historical background, principles, and applications. We discuss the role of natural products in traditional medicine and their potential benefits in modern healthcare. We also highlight the need for rigorous scientific research to validate the efficacy and safety of these products.

Chapter 2:
Chapter 2 focuses on the bio-analytical techniques used to characterize botanical products. We discuss the various methods employed, such as chromatography, spectroscopy, and microbiology, to identify and quantify the active compounds present in plants. We also explore the challenges associated with these techniques and the strategies used to overcome them.

Chapter 3:
Chapter 3 explores the use of botanical products in the treatment of various diseases. We review the literature on the efficacy and safety of these products in treating conditions such as cancer, diabetes, and cardiovascular disease. We also discuss the potential mechanisms of action and the challenges in developing botanical drugs.

Chapter 4:
Chapter 4 discusses the screening of biological activities of botanical products. We discuss the various screening methods employed, such as in vitro assays, in vivo models, and high-throughput screening techniques. We also explore the use of computer-aided drug design and virtual screening approaches to identify potential drug leads from botanical products.

Chapter 5:
Chapter 5 focuses on the issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. We review the literature on these topics and discuss the strategies used to ensure the quality and safety of herbal products. We also explore the challenges in regulating herbal drug development and the need for standardized protocols and regulations.

Conclusion:
In conclusion, this comprehensive volume explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine, along with their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.

Weight: 1274g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071626825
Edition number: 1st ed. 2023