Natural Products and Drug Discovery: An Integrated Approach

Natural products are essential for drug discovery, and combining traditional medicine with modern chemical technology can lead to more environmentally sound, economical, and effective processes. This book provides an applied overview of the field and highlights the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies.

Format: Paperback / softback
Length: 776 pages
Publication date: 23 February 2018
Publisher: Elsevier Health Sciences

Natural products have always played a vital role in drug discovery, but with the advancements in modern techniques and technologies, their significance has resurfaced. As researchers have gained the ability to identify, isolate, extract, and synthesize active compounds from natural sources in innovative ways, natural products are once again becoming a focal point in drug discovery. By combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs offers the potential to develop more environmentally friendly, cost-effective, and efficacious drug discovery processes.

Natural Products & Drug Discovery: An Integrated Approach delves into the current developments within this field, providing context to the ongoing shift and utilizing supportive case studies to showcase the challenges and achievements encountered by researchers in integrating traditional medicinal sources with modern chemical technologies. As such, it serves as a valuable resource for medicinal chemists, phytochemists, biochemists, pharmaceutical R&D professionals, and drug discovery students and researchers.

The book offers a comprehensive and applied overview of the field, spanning from traditional medicinal targets to cutting-edge molecular techniques. It begins by exploring the historical significance of natural products in drug discovery and their contribution to the development of modern medicine. The authors then delve into the various methods used to identify, isolate, and characterize natural products, including chromatography, spectroscopy, and bioassay techniques.

Furthermore, the book discusses the challenges and opportunities associated with using natural products as the basis for drugs. It highlights the need for efficient extraction and purification processes, as well as the challenges of identifying and characterizing active compounds from complex natural mixtures. The authors also address the issue of drug resistance and explore strategies for developing novel drug candidates that are resistant to existing therapies.

In addition to providing a theoretical framework, the book includes case studies that illustrate the practical applications of natural products in drug discovery. These case studies cover a wide range of therapeutic areas, including cancer, infectious diseases, and cardiovascular disorders, and showcase the successful integration of traditional medicinal knowledge with modern chemical technologies.

Overall, Natural Products and Drug Discovery: An Integrated Approach is a comprehensive and timely resource that provides a valuable perspective on the current state of natural products in drug discovery. It serves as a valuable reference for researchers, students, and professionals in the field, and will undoubtedly contribute to the ongoing development of this important area of research.

Weight: 1212g
Dimension: 152 x 229 x 41 (mm)
ISBN-13: 9780081020814