Necrotizing Enterocolitis, An Issue of Clinics in Perinatology

Dr. Caplan has assembled articles on necrotizing enterocolitis, with expert authors from top institutions contributing timely reviews on biomarker discovery, probiotics, pathophysiology, human milk, growth factors, fish oil, oral mother's milk, surgical management, epidemiology, and modifiable risk factors. Readers will gain scientific and medical information to improve patient outcomes.

\n Format: Hardback
\n \n Publication date: 08 March 2019
\n Publisher: Elsevier - Health Sciences Division
\n

Dr. Caplan, in collaboration with Dr. Lucky Jain, Consulting Editor, has brought together a comprehensive collection of articles dedicated to the latest clinical advancements in necrotizing enterocolitis (NEC). This esteemed team has assembled a panel of expert authors from renowned institutions to provide timely and insightful reviews on a range of critical topics.

Biomarker Discovery:

In this section, the authors explore the development of novel biomarkers that enhance early diagnostic capabilities, enabling timely intervention and improved patient outcomes. They discuss the significance of these markers in identifying NEC risk factors, predicting disease progression, and guiding treatment strategies.

Probiotics:

The authors delve into the current state-of-the-art research on probiotics and their potential role in preventing and treating NEC. They examine the effectiveness of different probiotic strains, dosage regimens, and delivery methods in mitigating NEC risk and promoting gut health.

NEC Pathophysiology:

Understanding the underlying mechanisms of NEC is crucial in developing effective treatment strategies. The authors explore how microbiome data is revolutionizing our understanding of NEC pathogenesis, shedding light on the interactions between gut bacteria, immune responses, and disease development.

Effect of Human Milk on NEC:

Human milk is considered a protective factor against NEC, but its impact on disease development remains understudied. The authors examine the latest research on the benefits of human milk in preventing and treating NEC, including its composition, immunological properties, and potential mechanisms of action.

Influence of Growth Factors on the Development of NEC:

Growth factors play a crucial role in infant development, but their association with NEC remains controversial. The authors explore the latest research on the influence of growth factors on NEC risk, including the role of insulin-like growth factor-1 (IGF-1) and other growth factors in gut development and NEC prevention.

Can Fish Oil Reduce the Incidence of NEC by Altering the Inflammatory Response?

Fish oil has been suggested as a potential protective agent against NEC due to its anti-inflammatory properties. The authors examine the evidence supporting the use of fish oil in reducing NEC incidence and its potential mechanisms of action.

Oral Mother's Milk:

Oral mother's milk is considered a valuable alternative to breast milk for preterm infants at high risk of NEC. The authors review the current state-of-the-art research on oral mother's milk and its influence on NEC prevention and treatment.

Does Surgical Management Alter the Outcome of NEC?

Surgical management is a critical aspect of NEC treatment, but its impact on disease outcome remains uncertain. The authors explore the latest research on surgical interventions, including surgical resection, intestinal anastomosis, and other surgical techniques, and their potential benefits in improving patient outcomes.

Epidemiology of NEC:

NEC is a complex disease with a significant impact on infant health. The authors examine the epidemiology of NEC, including its incidence, prevalence, and risk factors, and discuss the influence of PRBC transfusions and anemia on disease progression.

Role of Abdominal Ultrasound in Diagnosis of NEC:

Abdominal ultrasound is a non-invasive diagnostic tool that plays a crucial role in the early detection and management of NEC. The authors discuss the latest advancements in abdominal ultrasound technology, its accuracy in diagnosing NEC, and its potential applications in guiding treatment decisions.

Modifiable Risk Factors in NEC:

Identifying modifiable risk factors for NEC is essential in preventing disease development. The authors explore the latest research on modifiable risk factors, including preterm birth, low birth weight, maternal infections, and other factors that may increase the risk of NEC.

In conclusion, this comprehensive collection of articles provides readers with the scientific and medical knowledge they need to make informed clinical decisions and improve patient outcomes in the field of necrotizing enterocolitis. The expert authors' insights and perspectives shed light on the latest advancements in NEC research, treatment strategies, and risk management, empowering healthcare professionals to provide optimal care for infants at high risk of this devastating disease.

\n Weight: 398g\n
Dimension: 159 x 237 x 15 (mm)\n
ISBN-13: 9780323655347\n \n