Nitric Oxide Sensing

This book provides a comprehensive summary of recent state-of-the-art small-molecule probes and novel carbon nanomaterials used for chemical, photoluminescent, and electrochemical NO detection, with a dedicated chapter on devices for detecting NO in the human breath.

\n Format: Hardback
\n Length: 144 pages
\n Publication date: 17 September 2021
\n Publisher: Jenny Stanford Publishing
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Although nitric oxide (NO) is a vital biological signaling molecule, its free-radical electronic configuration renders it one of the most reactive and hazardous colorless gases, posing significant environmental and health risks. The detection of NO levels in biological samples and the atmosphere is of utmost importance. In recent years, substantial efforts have been dedicated to developing innovative active sensors and efficient devices for detecting and quantifying atmospheric NO, NO generated in biological samples, and NO exhaled in the human breath.

This comprehensive book serves as a valuable resource, summarizing the latest state-of-the-art small-molecule probes and novel carbon nanomaterials employed for chemical, photoluminescent, and electrochemical NO detection. Special attention is given to the available devices used for detecting NO in the human breath, which indirectly indicates lung inflammation. The authors, with expertise spanning various domains, have made concerted efforts to encompass nearly all aspects of NO sensing.

The significance of NO as a biological signaling molecule is well established, and its detection plays a crucial role in various fields, including medicine, environmental science, and atmospheric research. The free-radical electronic configuration of NO makes it highly reactive, leading to its involvement in various chemical reactions and interactions with other molecules. This reactivity also contributes to the colorless nature of NO, as it does not absorb visible light, making it difficult to detect without specialized equipment.

In biological samples, the detection of NO is particularly important in understanding various physiological processes and diseases. For instance, NO is involved in regulating blood flow, immune responses, and pain perception. By measuring NO levels in biological samples, researchers can gain insights into the underlying mechanisms of these processes and develop new therapies for diseases related to NO dysregulation.

Similarly, in the atmosphere, the detection of NO is essential for understanding the impact of human activities on the environment. NO is a greenhouse gas that contributes to climate change, and its levels in the atmosphere can be used as an indicator of air quality and environmental pollution. By monitoring NO levels, scientists can identify sources of pollution and develop strategies to mitigate their effects.

In recent years, significant advancements have been made in the development of active sensors and effective devices for detecting and quantifying atmospheric NO. These sensors utilize various techniques, such as chemiluminescence, electrochemistry, and optical spectroscopy, to measure NO levels with high sensitivity and precision. The use of these devices has enabled researchers to study NO dynamics in different environments, including urban areas, forests, and agricultural regions.

One area of particular interest in NO sensing is the detection of NO in the human breath. NO is exhaled in the human breath as a result of various physiological processes, including the breakdown of nitrates in the blood. By measuring NO levels in the human breath, researchers can indirectly infer the presence of lung inflammation, a condition that is associated with various respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD).

Several devices have been developed for detecting NO in the human breath, including gas chromatography, mass spectrometry, and electrochemical sensors. These devices rely on the detection of NO molecules after they have been exhaled and captured by a sampling device. The analysis of the captured NO molecules provides information about the concentration and composition of NO in the breath, which can be used to diagnose and monitor lung inflammation.

In conclusion, nitric oxide (NO) is a vital biological signaling molecule with significant environmental and health hazards. The detection of NO levels in biological samples and the atmosphere is crucial for understanding various physiological processes and diseases. In recent years, significant advancements have been made in the development of active sensors and effective devices for detecting and quantifying atmospheric NO. This book provides a comprehensive summary of recent state-of-the-art small-molecule probes and novel carbon nanomaterials used for chemical, photoluminescent, and electrochemical NO detection. Special attention is given to the available devices used for detecting NO in the human breath, which indirectly indicates lung inflammation. The authors with expertise in diverse dimensions have attempted to cover almost all areas of NO sensing, making this book a valuable resource for researchers and practitioners in the field.

\n Weight: 384g\n
Dimension: 157 x 237 x 14 (mm)\n
ISBN-13: 9789814877671\n \n