Nonhuman Primate Models in Preclinical Research. Volume 2: Disease Models

Non-human primates (NHP) are essential animal models for studying human diseases due to their close phylogenetic relationship and shared susceptibility. They contribute to our understanding of various diseases, biological phenomena, and the development of new therapies, treatments, drugs, and vaccines. This book covers important disease areas where NHP are used, such as infectious diseases, aging, neurodegenerative disorders, organ transplantation, and cancer.

Format: Hardback
Length: 368 pages
Publication date: 01 September 2021
Publisher: Nova Science Publishers Inc

Despite numerous encouraging advancements in the realm of animal-free technologies, the demand for well-defined animal models remains unwavering in order to comprehensively study fundamental properties of human diseases and devise innovative prophylactic and therapeutic interventions. Non-human primates (NHPs) constitute a modest yet significant fraction of the overall animal population utilized in biomedical and preclinical research. Their close phylogenetic relationship and shared susceptibility to numerous human diseases render them invaluable research models for investigating these ailments, thereby playing a pivotal role in advancing diverse branches of the medical field. Extensive studies conducted in NHPs have yielded valuable insights into a wide range of diseases and fundamental biological phenomena, and they continue to hold immense importance in the development of novel therapies, treatments, drugs, and vaccines. Moreover, NHP models also contribute to our broader understanding of the mechanisms underlying both non-disease and disease conditions. Several critical areas where NHPs can provide indispensable information include emerging infectious diseases, organ transplantation, neurological and aging-related disorders. While time constraints prevent comprehensive coverage in this book, the recent SARS-CoV-2 pandemic has vividly demonstrated the indispensable need for, and benefits of, NHP models.

The present volume, serving as the second installment of a two-part series, focuses on significant disease domains where NHPs serve as model species. Within this comprehensive volume, readers will find a diverse array of chapters dedicated to NHP models in infectious diseases, aging, neurodegenerative disorders, organ transplantation, and cancer. By delving into these diverse topics, this book aims to provide a comprehensive understanding of the invaluable contributions made by NHPs in advancing medical research and improving human health outcomes.

Weight: 850g
Dimension: 184 x 261 x 29 (mm)
ISBN-13: 9781536199147