Novel Platforms for Drug Delivery Applications

Novel Platforms for Drug Delivery Applications is a book that explores the design, synthesis, and characterization of novel drug delivery platforms and devices. It covers various materials and molecular platforms, such as hydrogels, nanocarriers, metal-organic-frameworks, ?-cyclodextrin, and polyphosphazene, discussing their benefits, limitations, and toxicological and safety implications.

Format: Paperback / softback
Length: 665 pages
Publication date: 14 October 2022
Publisher: Elsevier Science Publishing Co Inc

Novel Platforms for Drug Delivery Applications delves into intricate aspects of designing, synthesizing, and characterizing innovative drug delivery platforms and devices. This comprehensive volume provides a detailed account of the development, application, and performance of diverse novel molecular frameworks, serving as powerful drug delivery vehicles. The chapters encompass a wide array of materials and molecular platforms, including hydrogels, nanocarriers, metal-organic frameworks, ?-cyclodextrin, and polyphosphazene. Each chapter explores the advantages and limitations of each drug delivery system, as well as the toxicological and safety considerations. This book adopts an interdisciplinary approach, seamlessly bridging the fields of materials science and pharmacology, to address this rapidly evolving topic.

The utilization of novel drug delivery platforms has gained significant attention in recent years due to their potential to improve therapeutic outcomes and address various medical challenges. These platforms encompass a wide range of materials and techniques, such as hydrogels, nanocarriers, metal-organic frameworks, ?-cyclodextrin, and polyphosphazene, among others. Hydrogels, for instance, are highly versatile biomaterials that can be tailored to possess specific properties, such as swelling behavior, degradation rate, and drug release kinetics. They have been extensively studied for their ability to deliver drugs in a controlled manner, mimicking the natural tissue environment. Nanocarriers, on the other hand, are tiny particles or molecules that can be designed to target specific cells or tissues and deliver drugs with high efficiency. They can be modified with various functional groups, such as polymers, lipids, or proteins, to enhance their stability, biocompatibility, and drug payload capacity. Metal-organic frameworks (MOFs) are highly porous materials that possess a large surface area and can accommodate a wide range of drugs. They have been utilized for drug delivery applications, such as cancer therapy and targeted drug delivery, due to their ability to selectively release drugs in response to specific stimuli. ?-Cyclodextrin is a cyclic oligosaccharide that can encapsulate and deliver drugs through its hydrophobic core. It has been used in various drug delivery applications, including oral administration, injection, and topical application, due to its ability to improve drug solubility, stability, and bioavailability. Polyphosphazene is a polymeric material that can be modified to possess specific properties, such as self-assembly, flexibility, and drug release kinetics. It has been explored for its potential to deliver drugs in a controlled manner, particularly for cancer therapy and targeted drug delivery.

In conclusion, novel drug delivery platforms have emerged as powerful tools in the field of medicine. These platforms offer a wide range of advantages, including improved drug targeting, increased drug stability, and enhanced drug efficacy. By utilizing various materials and techniques, researchers and pharmaceutical companies can develop innovative drug delivery systems that can improve patient care and outcomes. However, it is important to carefully evaluate the safety and efficacy of these platforms before their clinical application.

Dimension: 229 x 152 (mm)
ISBN-13: 9780323913768