Oral Delivery of Therapeutic Peptides and Proteins

Oral Delivery of Therapeutic Peptides and Proteins provides an overview of the journey scientists pursue to attain protein and peptide oral delivery, highlighting the physiological challenges and overcoming protease inhibition and acid stability issues. It covers formulation technologies, modification of actives, animal models, and in vitro models.

Format: Paperback / softback
Length: 420 pages
Publication date: 01 August 2022
Publisher: Elsevier Science Publishing Co Inc

Oral Delivery of Therapeutic Peptides and Proteins is a comprehensive guide that delves into the intricate journey scientists undertake to achieve effective protein and peptide oral delivery. The book underscores the physiological complexities that must be considered alongside addressing the challenges of protease inhibition and acid stability, which are prevalent in this field of research. Key topics covered include the various formulation technologies being employed for oral delivery of proteins and peptides, strategies to modify active compounds to enhance their oral bioavailability, limitations of animal models in assessing oral bioavailability, and the use of in vitro models to simulate drug absorption and transport. This resource is invaluable for academics and industry researchers involved in formulation development, as well as advanced students in biotechnology and pharmacy who seek to gain deeper insights into this field.

Dimension: 235 x 191 (mm)
ISBN-13: 9780128210611