Organ-on-a-Chip: Methods and Protocols

This book provides a collection of microphysiological systems employed for chemical/drug screening and strategies to mimic various physiological conditions, written in the format of the highly successful Methods in Molecular Biology series.

Format: Paperback / softback
Length: 322 pages
Publication date: 16 September 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive book offers a valuable resource for researchers seeking to employ microphysiological systems for chemical/drug screening and to mimic various physiological conditions. It is organized into chapters that guide readers through Organ-on-a-Chip (OoC) platforms, including liver, intestine, blood-brain barrier, kidney, vessels, cardiac, and skeletal muscles, as well as articular joints and human fat. Additionally, the book delves into microfabrication technologies used to fabricate OoC devices, such as standard photo- and soft-lithography, techniques for fabricating membranes, and industrial-oriented fabrication methods. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, a list of necessary materials and reagents, tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Organ-On-a-Chip: Methods and Protocols aims to serve as a practical guide for researchers to advance their understanding and research in this field. By providing a comprehensive overview of microphysiological systems, OoC platforms, and microfabrication technologies, this book empowers researchers to explore new avenues for drug discovery, disease modeling, and personalized medicine.

Weight: 640g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071616956
Edition number: 1st ed. 2022