Oxidative Stress: Its Mechanisms, Impacts on Human Health and Disease Onset

Oxidative stress (OS) is a major factor in the onset of many diseases, and this book explores the causes, prevention, and consequences of OS. It covers chemical exposures and environmental factors, disease hallmarks and biomarkers, disease clusters, co-morbidities, free radical attacks, and the Oxidative Stress Index tool.

Format: Paperback / softback
Length: 500 pages
Publication date: 01 September 2022
Publisher: Elsevier Science & Technology

Oxidative stress (OS) is a significant factor in the development of human health and disease. This comprehensive text examines all known factors that contribute to elevated OS levels and the mechanisms by which OS leads to disease onset. The book covers a wide range of topics, including the causes and prevention of oxidative stress, the types of chemical exposures and environmental factors that precipitate disease, disease hallmarks and biomarkers, disease clusters, disease co-morbidities, free radical attacks at the cellular level, and the Oxidative Stress Index tool, which is used to identify the primary causes of specific diseases and predict the likelihood of disease onset.

Section one explores the causes and prevention of oxidative stress, including the role of lifestyle factors, diet, and genetics. It also discusses the impact of stress on OS and the mechanisms by which stress can exacerbate disease symptoms.

Section two examines the types of chemical exposures and environmental factors that precipitate disease, including air pollution, water pollution, and occupational exposure to chemicals. It also discusses the mechanisms by which these exposures can damage cells and lead to disease development.

Section three explores disease hallmarks and biomarkers, including the markers of oxidative stress, inflammation, and cellular damage that are associated with various diseases. It also discusses the use of these markers in diagnosis, treatment, and disease management.

Section four examines disease clusters, including the association between certain diseases and specific environmental factors, such as smoking, diet, and alcohol consumption. It also discusses the potential for disease prevention and intervention strategies in these clusters.

Section five explores disease co-morbidities, including the relationship between multiple diseases and the risk of developing additional diseases. It also discusses the challenges of managing co-morbid conditions and the importance of holistic healthcare approaches.

Section six examines free radical attacks at the cellular level, including the role of antioxidants and other cellular defense mechanisms in protecting cells from damage. It also discusses the potential for oxidative stress to contribute to the development of cancer and other chronic diseases.

Section seven introduces the Oxidative Stress Index tool, which is used to identify the primary causes of specific diseases and predict the likelihood of disease onset. It discusses the premise of the tool and how it can be used to develop personalized disease prevention and treatment strategies.

In conclusion, Oxidative Stress: Its Impact on Human Health and Disease Onset is a valuable resource for researchers, scientists, health practitioners, public health professionals, and others who wish to broaden their knowledge on this important topic. With comprehensive coverage of not only the impact of OS due to chemical exposure but also the consequences of environmental factors, this book provides a comprehensive understanding of the factors that contribute to human health and disease development. By exploring the causes, prevention, and management of oxidative stress, this text helps to promote healthier lifestyles and reduce the risk of developing chronic diseases.

Dimension: 235 x 191 (mm)
ISBN-13: 9780323918909