Paraneoplastic Neurologic Disorders

Paraneoplastic Neurological Disorders, Volume 200 explores autoantibodies against neuronal cell surface antigens, immuno-oncological drugs, and the introduction of new drugs used in immune checkpoint inhibitor cancer therapy. It also investigates the pathogenetic mechanisms of these disorders, individual syndromes of the CNS, PNS, NMJ, and muscle, and the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Side effects of the new immuno-oncological drugs are also covered.

Format: Hardback
Length: 496 pages
Publication date: 25 April 2024
Publisher: Elsevier Science Publishing Co Inc

Paraneoplastic neurological disorders (PNDs) are a group of diseases characterized by the presence of autoantibodies against neuronal cell surface antigens, which can lead to a wide range of neurological symptoms. Volume 200 of Paraneoplastic Neurological Disorders covers new and recent descriptions of these autoantibodies, as well as the introduction of new immuno-oncological drugs that can contribute to diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. The book explores the pathogenetic mechanisms of these disorders, as well as the immunopathogenesis of immune checkpoint inhibitor cancer therapy. It also presents individual syndromes of the central nervous system (CNS), peripheral nervous system (PNS), neuromuscular junction (NMJ), and muscle, and investigates the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Additionally, the book covers the side effects of the new immuno-oncological drugs increasingly used in cancer therapy.

Dimension: 262 x 192 (mm)
ISBN-13: 9780128239124