Parathyroid Glands in Chronic Kidney Disease

This book provides practical strategies for diagnosing and treating parathyroid disease in chronic kidney disease, covering anatomy, physiology, diagnostic tests, and therapies. It is a valuable resource for nephrologists, endocrinologists, endocrine surgeons, and family medicine physicians.

Format: Paperback / softback
Length: 196 pages
Publication date: 08 May 2021
Publisher: Springer Nature Switzerland AG

This comprehensive book offers invaluable insights and practical strategies for nephrologists and endocrinologists in accurately diagnosing and effectively treating the diverse manifestations of parathyroid disease that arise in the context of chronic kidney disease. Spanning several chapters, it delves into intricate details of parathyroid gland anatomy and physiology, while also exploring diagnostic tests and their specific nuances in chronic disease management. The book underscores the diverse range of therapeutic approaches employed for managing secondary hyperparathyroidism, and critically evaluates the latest research developments in the field. By presenting a thorough review of the current literature, encompassing advancements in medical and surgical treatments as well as current indications for parathyroidectomy, this practice-oriented resource serves as an indispensable tool for nephrologists, endocrinologists, endocrine surgeons, and family medicine physicians.

Introduction:
Parathyroid disease is a complex endocrine disorder that affects the regulation of calcium and phosphate levels in the body. It is commonly associated with chronic kidney disease (CKD), where the kidneys are unable to adequately filter waste products and regulate electrolyte levels. As a result, parathyroid hormone (PTH) levels increase, leading to bone mineralization, muscle weakness, and other complications.

Diagnosis and Treatment:
The diagnosis of parathyroid disease involves a combination of clinical examination, imaging tests, and laboratory measurements. Imaging techniques such as ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) can help identify the location and size of the parathyroid glands. Laboratory tests, including serum calcium, phosphate, and PTH levels, can aid in the confirmation of the diagnosis and guide treatment decisions.

Therapeutic Approaches:
The treatment of parathyroid disease depends on the underlying cause and severity of the condition. In cases of secondary hyperparathyroidism, which is the most common form, medications such as calcium channel blockers, vitamin D analogs, and renin-angiotensin system inhibitors are commonly used to reduce PTH levels. In some cases, surgery may be necessary to remove the affected parathyroid gland(s).

Research and Innovation:
Recent research has focused on developing new treatments and therapies for parathyroid disease. One area of interest is the use of gene therapy, which involves introducing genetic material into the parathyroid glands to correct the underlying genetic defect. Other research is exploring the use of stem cells to regenerate damaged parathyroid tissue.

Conclusion:
Parathyroid disease is a significant complication of CKD, and early diagnosis and treatment are essential for preventing complications and improving patient outcomes. This comprehensive book provides valuable insights and practical strategies for nephrologists and endocrinologists in accurately diagnosing and effectively treating the diverse manifestations of parathyroid disease that arise in the context of chronic kidney disease. By staying up-to-date with the latest research and therapeutic advancements, healthcare professionals can provide optimal care for their patients with parathyroid disease.

Weight: 454g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030437718
Edition number: 1st ed. 2020