Peptide and Protein Drug Delivery Using Polysaccharides

This book discusses the use of polysaccharides in peptide and protein drug delivery, covering their production, absorption, metabolism, and excretion. It also includes analytical methods for detection in tissue fluids and homogenates. Therapeutic polysaccharides discussed include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar, myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen, and dextran.

Format: Paperback / softback
Length: 330 pages
Publication date: 10 October 2023
Publisher: Elsevier Science Publishing Co Inc

Peptide and Protein Drug Delivery Using Polysaccharides presents a comprehensive and interdisciplinary exploration of the application of polysaccharides in the field of peptide and protein drug delivery. This book delves into the fundamental biology of various polysaccharides of current interest, encompassing their production at both pilot and large-scale stages using diverse techniques such as cell and hairy root cultures. Additionally, it examines the factors influencing polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with a special focus on vaccine absorption, metabolism, and drug delivery. The final section explores analytical methods for detecting these compounds in tissue fluids and homogenates. Throughout the text, accessible figures, tables, and graphical abstracts are provided to enhance understanding.

Therapeutic polysaccharides discussed in this book include cellulose, hyaluronic acid, heparin, carrageenan, alginic acid, agar, myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen, and dextran. These polysaccharides have shown promising potential in drug delivery applications due to their unique properties, such as biocompatibility, biodegradability, and ability to enhance drug absorption and stability.

Peptide and Protein Drug Delivery Using Polysaccharides serves as a valuable resource for researchers, scientists, and pharmaceutical professionals interested in developing innovative drug delivery systems using polysaccharides. It provides a comprehensive understanding of the biological aspects, production techniques, and analytical methods related to polysaccharide-based drug delivery, enabling the development of more effective and targeted therapeutics.

Weight: 702g
Dimension: 191 x 235 x 23 (mm)
ISBN-13: 9780443189258