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Peptide Macrocycles: Methods and Protocols

Peptide Macrocycles: Methods and Protocols

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  • More about Peptide Macrocycles: Methods and Protocols

This book explores the latest techniques and strategies used to study peptide macrocycles, including synthesis, combinational library synthesis and screening, characterization, and unique applications. It is written in the Methods in Molecular Biology series format and is a valuable resource for researchers looking to learn more about this developing field.

Format: Paperback / softback
Length: 469 pages
Publication date: 02 October 2022
Publisher: Springer-Verlag New York Inc.


This comprehensive volume delves into the latest techniques and strategies employed in the field of peptide macrocycles. The book is organized into four distinct parts, each covering a different aspect of peptide macrocycle research.

Part One explores various methods for peptide cyclization, providing a thorough understanding of the synthesis of these complex molecules. Part Two focuses on the creation of combinatorial libraries of peptide macrocycles and their screening against biological targets of interest.

Part Three delves into the study and characterization of peptide macrocycle-target interactions, shedding light on the molecular mechanisms underlying these interactions. Part Four introduces unique applications of peptide macrocycles, ranging from higher-order structure formation to post-synthetic functional modifications.

Written in the highly successful Methods in Molecular Biology series format, the chapters in this book include comprehensive introductions to their respective topics, detailed lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and helpful tips on troubleshooting and avoiding common pitfalls.

Peptide Macrocycles: Methods and Protocols is an invaluable resource for both novice and experienced researchers seeking to expand their knowledge in this rapidly evolving field. With its cutting-edge and comprehensive coverage, this book is sure to become a staple in the libraries of scientists and researchers working in peptide chemistry and molecular biology.

Weight: 913g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071616918
Edition number: 1st ed. 2022

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