TomasKoltai,LarryFliegel,Stephan J.Reshkin,Fatima, School of Medicine, University of Minho, Braga, Portugal) Baltazar,Rosa AngelaCardone,Khalid Omer, PhDAlfarouk,Julieta, School of Medicine, University of Minho, Portugal) Afonso
pH Deregulation as the Eleventh Hallmark of Cancer
pH Deregulation as the Eleventh Hallmark of Cancer
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Excellent- More about pH Deregulation as the Eleventh Hallmark of Cancer
pH Deregulation as the Eleventh Hallmark of Cancer highlights the importance of pH deregulation in cancer and discusses various mechanisms and clinical implications. It suggests that treating pH abnormalities can enhance the effectiveness of classical cancer treatments and proposes pH deregulation as an additional characteristic to evaluate and fight cancer.
Format: Paperback / softback
Length: 190 pages
Publication date: 01 August 2023
Publisher: Elsevier Science Publishing Co Inc
pH Deregulation as the Eleventh Hallmark of Cancer presents key concepts about pH deregulation in a concise and straight-forward manner. The book discusses topics such as pH regulation and metabolism, sodium hydrogen exchanger, monocarboxylate transporter, V-ATPase proton pump, carbonic anhydrases, and voltage gated sodium channels. In addition, it covers clinical and therapeutic implications and future perspectives. This is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the role of pH deregulation in cancer treatment.
pH deregulation can improve the outcome of classical treatments without adding toxicity to them, and the book shows that treating the pH peculiarities of cancer is simple and can be performed with existing drugs. Based on the classification of tumor malignancy in ten hallmarks, the authors put pH deregulation at the spotlight and separated from metabolic reprogramming due to its impact on all other hallmarks, proposing it as an additional characteristic to evaluate and fight cancer.
Weight: 538g
Dimension: 212 x 276 x 13 (mm)
ISBN-13: 9780443154614
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