Shulph Ink
Physiological Consequences of Brain Insulin Action
Physiological Consequences of Brain Insulin Action
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Excellent- More about Physiological Consequences of Brain Insulin Action
The brain is essential for metabolism and behavior, and insulin modulates brain function and affects energy metabolism and cognition. Alzheimer's disease patients exhibit brain insulin resistance with perturbed brain metabolism. This book covers insulin signaling in the brain, insulin resistance, and the association between brain insulin resistance and neurodegenerative diseases. It also discusses potential behavioral and pharmacological approaches to support brain insulin signaling.
Format: Hardback
Length: 244 pages
Publication date: 06 September 2022
Publisher: Taylor & Francis Ltd
The brain plays a vital role in regulating both whole-body metabolism and behavior. One important hormone that influences brain function and affects energy metabolism, cognition, and satiety is insulin, which is derived from the pancreas. Insulin modulates various brain cell populations, including those involved in satiety and reward, to achieve its effects. However, in Alzheimer's disease, there is a signature of brain insulin resistance, accompanied by perturbed brain metabolism. This book aims to provide an in-depth understanding of insulin signaling in the brain and its implications for brain function, metabolism, and behavior. It will cover the basics of insulin signaling, including the mechanisms by which insulin binds to its receptor and triggers downstream signaling pathways. It will also discuss concepts of insulin resistance, a feature of type 2 diabetes, and its impact on brain function. Insulin's effects on cognitive function will be explored, and the association between brain insulin resistance and neurodegenerative diseases such as Alzheimer's will be discussed. Additionally, potential behavioral and pharmacological concepts that can affect brain insulin signaling will be summarized. By understanding the role of insulin in the brain, researchers and healthcare professionals can develop new strategies to support brain health and prevent neurodegenerative diseases.
Weight: 657g
Dimension: 254 x 178 (mm)
ISBN-13: 9780367529482
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