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Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan

Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan

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  • More about Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan

Polycystic Ovary Syndrome (PCOS) is a complex chronic condition that affects adult women and adolescent girls. This book provides a comprehensive, evidence-based approach to diagnosis, treatment, and management across the lifespan, covering all aspects of PCOS, including short- and long-term metabolic, endocrine, and psychological challenges. It offers an integrative approach to understanding pathophysiology and management, with a focus on genetics, microRNAs, and risk factors. The book includes clinical, hormonal, and metabolic features, diagnostic criteria, and PCOS phenotypes. It presents treatment and management options for common symptoms, hirsutism, menstrual irregularity, and conception planning, including a chapter on subfertility and the male PCOS equivalent. It also addresses standard comorbidities and global approaches to patients with PCOS, including the use of complementary/alternative medicine, lifestyle modification, and behavioral therapy. An eBook version is included with purchase.

Format: Paperback / softback
Length: 320 pages
Publication date: 14 February 2023
Publisher: Elsevier - Health Sciences Division


Polycystic Ovary Syndrome (PCOS) is a complex chronic condition that affects women of reproductive age. It is characterized by a range of symptoms, including irregular menstrual cycles, hirsutism (excessive hair growth), acne, and infertility. PCOS is a multifactorial disorder, with genetic, environmental, and hormonal factors playing a role in its development.

This comprehensive book provides a holistic and global approach to all aspects of PCOS, from basic science to clinical advances across the lifespan. It offers authoritative guidance on the diagnosis, treatment, and management of this challenging syndrome.

The book begins with an introduction to the pathophysiology of PCOS, including the role of insulin resistance, androgen excess, and inflammation. It then discusses the diagnostic criteria and phenotypes of PCOS, including the Rotterdam criteria, the Androgen Excess and Polycystic Ovary Syndrome Society (AEPOS) criteria, and the National Institute of Health (NIH) criteria.

The book goes on to cover all aspects of PCOS management across the lifespan, including short- and long-term metabolic, endocrine, and psychological challenges. It provides an integrative approach to the understanding of pathophysiology and management of PCOS in adult women and adolescent girls, with a focus on genetics, microRNAs, and risk factors.

Clinical, hormonal, and metabolic features of PCOS are extensively discussed, including the effects of insulin resistance, hyperandrogenism, and inflammation on reproductive health, metabolic function, and cardiovascular disease. Diagnostic criteria and PCOS phenotypes are also covered, including the use of ultrasound imaging, hormonal assays, and genetic testing.

Treatment and management options for common symptoms of PCOS, such as hirsutism, menstrual irregularity, and acne, are presented. The book includes a chapter on subfertility and the male PCOS equivalent, discussing the use of assisted reproductive technologies, lifestyle modification, and behavioral therapy in managing PCOS.

Standard comorbidities associated with PCOS, such as type 2 diabetes and cardiovascular disease, are also covered, along with a section on global approaches to patients with PCOS that addresses unique concerns, practices, and stigmas associated with how different cultures approach the disorder.

The book also addresses the use of complementary/alternative medicine, lifestyle modification, and behavioral therapy in managing PCOS. It provides evidence-based recommendations for these interventions and discusses their potential benefits and risks.

An eBook version of the book is included with purchase, allowing readers to access all of the text, figures, and references, with the ability to search, customize their content, make notes and highlights, and have content read aloud.

In conclusion, Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan is a comprehensive and practical resource for endocrinologists, fertility specialists, gynecologists, and internists who diagnose and treat patients with PCOS. It provides a coherent and evidence-based approach to diagnosis, treatment, and management of this complex chronic condition, covering all aspects of PCOS and management across the lifespan. The book offers an integrative approach to the understanding of pathophysiology and management of PCOS, with a focus on genetics, microRNAs, and risk factors. It provides decision-making tools for endocrinologists, fertility specialists, gynecologists, and internists who diagnose and treat patients with this complex chronic condition.

Weight: 600g
Dimension: 216 x 282 x 13 (mm)
ISBN-13: 9780323879323

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