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Post-transcriptional Gene Regulation in Human Disease
Post-transcriptional Gene Regulation in Human Disease
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- More about Post-transcriptional Gene Regulation in Human Disease
Post-transcriptional Gene Regulation in Human Disease provides a comprehensive overview of post-transcriptional genetic control mechanisms and their roles in various pathologies and developmental outcomes. It discusses epigenetic mechanisms, RNA binding proteins, evolution, and methods to study these mechanisms. The second half explores specific diseases and therapeutic targets.
Format: Paperback / softback
Length: 394 pages
Publication date: 01 August 2022
Publisher: Elsevier Science & Technology
Post-transcriptional Gene Regulation in Human Disease, a groundbreaking addition to the Translational Epigenetics book series, provides a comprehensive exploration and analysis of the intricate mechanisms underlying post-transcriptional genetic control and their profound impact on diverse pathologies and human developmental outcomes. Spanning two substantial parts, this authoritative text delves into the foundational aspects of post-transcriptional gene regulation, encompassing epigenetic mechanisms, RNA binding proteins, the evolution of this regulatory process, and methodologies employed to study these mechanisms.
The first half of the book offers a foundational understanding of post-transcriptional gene regulation, including alternative splicing, polyadenylation, mRNA stability, and the crucial role of microRNAs in disease progression. Detailed examinations are conducted to unravel the intricate mechanisms by which these events influence gene expression and contribute to the development of various diseases.
In the second half, the book delves into a deeper discussion of post-transcriptional gene regulation in specific diseases, highlighting the therapeutic implications and potential targets. By examining the role of post-transcriptional events in cancer, cardiovascular diseases, neurological disorders, and other pathologies, researchers and clinicians gain valuable insights into developing targeted therapies and interventions.
This comprehensive volume serves as a valuable resource for researchers, clinicians, and students interested in understanding the complexities of post-transcriptional gene regulation and its implications for human health. By unraveling the mechanisms underlying these processes, researchers can develop innovative approaches to diagnose, treat, and prevent diseases, leading to improved patient outcomes and a better understanding of the underlying biology of human diseases.
Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780323913058
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