Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development is a valuable reference for difficult-to-solve challenges in the pharmaceutical industry. It provides chromatographic theory, case studies, and examples from experts. The book helps readers align HPLC/UHPLC capabilities with SFC as an orthogonal tool, highlighting its applications in routine and challenging separative methods. It is particularly useful for experienced HPLC users and newcomers to separation science.

Format: Paperback / softback
Length: 432 pages
Publication date: 09 December 2022
Publisher: Elsevier - Health Sciences Division

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development is a comprehensive and invaluable resource for addressing complex challenges in pharmaceutical analysis. This comprehensive text offers a valuable "go-to" reference for researchers and practitioners facing challenging chromatographic problems. It provides a solid foundation of chromatographic theory, complemented by first-hand case studies and examples drawn from academic and industry experts. Moreover, this text serves as an essential teaching tool for professors introducing analytical instrumental courses, allowing students to learn about one of the most sustainable and powerful separation methods currently available. While the text's applications span various industrial sectors, it primarily focuses on its use in the pharmaceutical industry. The book's design enables readers to seamlessly integrate current HPLC/UHPLC capabilities with supercritical fluid chromatography (SFC) as an orthogonal tool for project-specific methods. It highlights the versatility of SFC in routine and challenging separative methods, placing it on the spectrum of useful chromatographic tools. Whether you are an experienced HPLC user seeking to expand your knowledge in orthogonal separation techniques or a newcomer to the field of separation science, this text is particularly valuable. Chapters address the specific analytical needs of the pharmaceutical industry, outlining where SFC excels and where it may not be the most suitable approach. Readers will gain a deep understanding of how and where SFC can be applied and adapted more routinely across the pharmaceutical industry, promoting a greener and more efficient approach to separation opportunities and challenges. The pharmaceutical industry encompasses various stages, including early drug discovery, process chemistry, and late-stage development and manufacturing. SFC finds applications in these areas, contributing to the advancement of drug research, development, and production. By leveraging the unique properties of supercritical fluids, SFC enables the efficient separation of complex mixtures, providing valuable insights into the composition, purity, and stability of pharmaceutical products. Overall, Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development is a must-have resource for anyone involved in pharmaceutical analysis. It offers a comprehensive and practical approach to addressing complex challenges, equipping researchers and practitioners with the knowledge and tools necessary to succeed in their endeavors.

Dimension: 235 x 191 (mm)
ISBN-13: 9780323884877