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Progress in the Chemistry of Organic Natural Products 115
Progress in the Chemistry of Organic Natural Products 115
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Excellent- More about Progress in the Chemistry of Organic Natural Products 115
This book explores the potential of natural products as treatments for cancer, leishmaniasis, and infectious diseases, including malaria and trypanosomiasis. It also highlights the role of total synthesis in revising structures proposed for decanolides and developing potent inhibitors of SERCA.
Format: Paperback / softback
Length: 203 pages
Publication date: 03 April 2022
Publisher: Springer Nature Switzerland AG
This comprehensive book delves into the current understanding and remarkable progress made in the field of natural products. It begins by exploring the potential role of total synthesis in revising the structures proposed for decanolides, ten-membered lactones primarily found in fungi, frogs, and termites. The subsequent chapter introduces the development of thapsigargin, a captivating plant-derived sesquiterpene lactone, which holds immense promise as a potent inhibitor of the enzyme SERCA (sarco-endoplasmic Ca 2+ ATPase). This enzyme plays a crucial role in regulating cellular calcium levels, making thapsigargin a promising lead compound in the treatment of cancer.
The third chapter delves into the potential of various plant phenolic compounds to combat the tropical and sub-tropical infectious disease known as leishmaniasis. Furthermore, this volume showcases recent advancements related to the plant alkaloid, cryptolepine, which holds significant interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Through its detailed exploration, this book provides valuable insights into the diverse world of natural products and their potential applications in medicine. It serves as a valuable resource for researchers, scientists, and healthcare professionals seeking to advance their knowledge in this field.
Weight: 338g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030648558
Edition number: 1st ed. 2021
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