Protein Reviews: Volume 22

The Protein Reviews series publishes reviews on protein structure, function, evolution, and genetics. Volume 22 includes six review chapters on important topics, such as carotenoid-protein interactions, non-continuum of eukaryotic transcriptional regulation, photoreceptor phosphodiesterase structure, rhodopsin modulators, HIV protease inhibition, and single-run catalysis and kinetic control of human telomerase holoenzyme. The volume is intended for research scientists, clinicians, physicians, and graduate students in these fields.

Format: Paperback / softback
Length: 132 pages
Publication date: 30 March 2023
Publisher: Springer Nature Switzerland AG

The Protein Reviews series serves as a vital platform for disseminating comprehensive reviews that delve into the intricate and critical aspects of protein structure, function, evolution, and genetics. These volumes are published online initially, followed by their print publication. The selection of chapters is based on their significance in understanding biological systems, addressing health and disease-related challenges, contributing to scientific and technological advancements, and fostering innovation.

Volume 22, in particular, presents a collection of six review chapters authored by esteemed experts in their respective fields. The first chapter delves into the intricate interplay between carotenoids and proteins, shedding light on their interactions and potential implications. Chapter two explores the non-continuum of eukaryotic transcriptional regulation, highlighting the complexities and mechanisms involved in gene expression control. The third chapter focuses on the structure and function of the regulatory and catalytic domains of the photoreceptor phosphodiesterase (PDE6) holoenzyme, a key player in visual perception. Chapter four examines the current knowledge surrounding small molecule compounds that have been evaluated as potential rhodopsin modulators, with the potential to develop novel therapies for retinitis pigmentosa. Chapter five explores the functionality associated with plasticity and the inhibition of the human immunodeficiency virus (HIV) protease, offering insights into potential therapeutic strategies. Finally, chapter six explores single-run catalysis and kinetic control of human telomerase holoenzyme, a crucial enzyme involved in telomere maintenance and cancer development.

This volume is designed to cater to a diverse audience, including research scientists, clinicians, physicians, and graduate students specializing in biochemistry, cell biology, molecular biology, immunology, and genetics. The comprehensive reviews presented herein provide valuable insights into the latest advancements and breakthroughs in protein research, paving the way for future discoveries and advancements in these fields.

Weight: 281g
Dimension: 254 x 178 (mm)
ISBN-13: 9783030964078
Edition number: 1st ed. 2022