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Shulph Ink

Proteinkinase Inhibitors

Proteinkinase Inhibitors

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  • More about Proteinkinase Inhibitors


This book provides a comprehensive and authoritative overview of the design and implementation of proteinkinase inhibitors, covering their function, structure, and topology, molecular modeling, selectivity, and cancer treatment. It also includes a case study on Receptor Tyrosine Kinases.

Format: Paperback / softback
Length: 256 pages
Publication date: 24 March 2022
Publisher: Springer Nature Switzerland AG


This comprehensive book delves into the principles of design and showcases successful implementations of proteinkinase inhibitors (PKIs). It provides a thorough and authoritative exploration of the field's history and latest advancements. Written by experts from industry and academia, the chapters cover various aspects of proteinkinases, including their function, structure, and topology. They also delve into molecular modeling techniques, highlighting strategies to achieve high levels of selectivity for kinase inhibitors. Additionally, the book explores the potential of kinase inhibitors in cancer treatment, with a special focus on inhibitors of c-Jun N-terminal kinase 3 and covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases (EGFR, VEGFR, PDGFR) is also presented, offering valuable insights into the application of PKIs in drug discovery.

With its extensive coverage, this book appeals to a wide range of readers, including medicinal chemists, students, researchers, and professionals alike. It serves as a valuable resource for those seeking to gain a deeper understanding of the principles and applications of PKIs in drug development and cancer therapy.

Weight: 409g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030681821
Edition number: 1st ed. 2021

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