Proteolytic Signaling in Health and Disease

Proteolytic enzymes have been studied in human development and pathologies, and Proteolytic Signaling in Health and Disease provides an in-depth discussion of their role. International chapter authors examine pathological conditions associated with proteolysis, and the book empowers new research with up-to-date analytical methods and protocols.

Format: Paperback / softback
Length: 308 pages
Publication date: 14 October 2021
Publisher: Elsevier Science & Technology

In recent years, propelled by advancing technologies and innovative experimental designs, groundbreaking studies have shed profound light on the regulatory significance of proteolytic enzymes throughout human development and various pathologies. Proteolytic Signaling in Health and Disease presents a comprehensive exploration of fundamental physiological and developmental processes governed by proteases, encompassing protein turnover, autophagy, antigen processing, presentation, and major histocompatibility complex (MHC) molecules. Embarking beyond the realm of basic biology, international chapter authors delve into a diverse array of pathological conditions linked to proteolysis, encompassing inflammation, wound healing, and cancer. Subsequent chapters delve into the newly unveiled interconnected network of proteases, known as the "protease web," and explore effective strategies for studying this intricate network. Moreover, this book equips researchers with cutting-edge analytical methods and detailed protocols to unravel the complexities of proteolytic signaling events. By unraveling the intricate mechanisms of proteolytic enzymes, this invaluable resource empowers researchers to gain a deeper understanding of human health and disease, paving the way for innovative therapeutic interventions and advancements in the field of medicine.

Weight: 610g
Dimension: 235 x 191 (mm)
ISBN-13: 9780323856966