Proteomics Approaches to Unravel Virus - Vertebrate Host Interactions

Proteomics Approaches to Unravel Virus-Vertebrate Host Interactions, Volume 109 in the Advances in Virus Research series, highlights state-of-the-art mass spectrometry techniques to elucidate the tight interplay of vertebrate viruses and their host cells.

Format: Hardback
Length: 264 pages
Publication date: 05 May 2021
Publisher: Elsevier Science Publishing Co Inc

Proteomics, a powerful tool in unraveling the intricate interactions between viruses and their vertebrate hosts, takes center stage in Volume 109 of the Advances in Virus Research series. This comprehensive volume showcases cutting-edge mass spectrometry techniques to delve into the complex dance between vertebrate viruses and their host cells. Within its pages, readers will find a treasure trove of knowledge, encompassing chapters on various aspects of virus-host interactions.

The first chapter delves into the realm of spatio-temporal resolution of host protein complexes during virus entry, shedding light on the dynamic processes that occur at the molecular level during this critical stage. The subsequent chapters explore proteomic approaches to investigate gammaherpesvirus biology and associated tumorigenesis, providing valuable insights into the mechanisms behind these viruses' pathogenicity.

Mass Spectrometry Imaging in Virus Research is another key topic covered in the volume. This innovative technique enables the visualization of virus-host interactions at the cellular level, providing a deeper understanding of the intricate dynamics that underpin viral infections.

The mapping of surfaceome dynamics during viral infection is another fascinating chapter, highlighting the role of the host's surface proteins in shaping the viral lifecycle and immune response. The characterization of proteolytic events in virus-host interactions sheds light on the molecular mechanisms employed by viruses to evade host defenses and manipulate host cells.

Dynamic protein network modulation upon viral infection is a crucial aspect of virus-host interactions, and the volume explores this topic in depth. It examines how viruses hijack host protein networks to their advantage, altering cellular processes and promoting viral replication.

Furthermore, the volume includes chapters on various other topics, such as the identification of viral proteins and peptides using mass spectrometry, the development of proteomic tools for virus detection and characterization, and the application of proteomics in vaccine development.

With its extensive coverage of state-of-the-art proteomics techniques and their applications in virus research, Volume 109 of the Advances in Virus Research series is a valuable resource for researchers, students, and healthcare professionals alike. It provides a comprehensive understanding of the complex interplay between viruses and their hosts, paving the way for new discoveries and advancements in the field.

Weight: 540g
Dimension: 229 x 152 (mm)
ISBN-13: 9780128230428