Pyrazolo Pyrimides-Based Drug Discovery

Pyrazolopyrimidines are important scaffolds for generating chemical libraries and drug-like candidates, with specific functional groups covered and synthesis of bioactive compounds against pathological conditions. This book is ideal for researchers in organic and medicinal chemistry.

Format: Paperback / softback
Length: 370 pages
Publication date: 01 March 2022
Publisher: Elsevier Science Publishing Co Inc

Pyrazolo Pyrimides-Based Drug Discovery delves into the medicinal properties of all isomeric forms of pyrazolopyrimidines, with a particular focus on their structure-activity relationship (SAR). These compounds hold significant importance in organic and medicinal chemistry as they serve as a crucial bridge between life sciences and biochemical investigations. Pyrazolopyrimidines are vital scaffolds for creating diverse chemical libraries and drug-like candidates, aimed at achieving desired therapeutic and pharmacological effects. Specific functional groups are explored, along with the synthesis of bioactive compounds targeting specific pathological conditions. Isomeric forms of pyrazolo pyrimidine, such as pyrazolo[5,1-b]pyrimidines, pyrazolo[5,1-a]pyrimidines, pyrazolo[4,3-d]pyrimidines, pyrazolo[1,5-c]pyrimidines, and pyrazolo[3,4-d]pyrimidines, are discussed in detail. Furthermore, this book provides essential information on functionalization and its impact, facilitating the discovery of pyrazolopyrimidine-based drug candidates. Whether you are a researcher working in organic and medicinal chemistry in academia or industry, this book is an invaluable resource for your studies and research endeavors.

Dimension: 229 x 152 (mm)
ISBN-13: 9780128238875