Radiotheranostics - A Primer for Medical Physicists I: Physics, Chemistry, Biology and Clinical Applications

This book covers radiotheranostics in cancer control, including the scientific, clinical, and educational aspects. It defines radiotheranostics, describes the history of radionuclide therapy and theranostics, and examines the clinical applications of unconjugated and radionuclide-conjugated cancer-specific vectors. It also discusses radioactivity measurements, traceability, instrumentation, and education, training, and competence of a multidisciplinary team. The second volume explores dosimetric and radiation safety.

Format: Hardback
Length: 214 pages
Publication date: 20 February 2024
Publisher: Taylor & Francis Ltd

This book delves into the multifaceted realm of radiotheranostics in cancer control, encompassing scientific, clinical, and educational aspects. It serves as a comprehensive resource, providing a solid foundation for understanding and applying radiotherapeutic techniques.

In the first volume, the authors establish the framework for radiotheranostics by defining the field and tracing its historical development, including the origins of radionuclide therapy and theranostics. They delve into the biology of cancer, shedding light on the mechanisms underlying tumor growth and the potential of radiotherapeutic agents to target cancer cells.

The book explores the clinical applications of unconjugated radionuclides, such as ¹³¹I and ²²³Ra, and radionuclide-conjugated cancer-specific vectors, including peptides, small molecules, antibodies, and nanoparticles. It discusses the use of these agents in various cancer therapies, including diagnostic imaging, radiation therapy, and targeted therapy. The authors also introduce clinical trials and drug development processes, highlighting the importance of rigorous research and clinical trials in advancing the field.

Furthermore, the book examines epidemiological studies and the adverse effects of radionuclide therapy, including radiation injuries and chemical toxicity. It provides valuable insights into the safety considerations and risk management strategies associated with radiotherapeutic interventions.

Volume I concludes with a comprehensive discussion on the education, training, and competence of a radiotheranostic multidisciplinary team. It summarizes the principal physics characteristics of theranostics today, highlighting areas that will be further explored in the second volume. The authors also offer a glimpse into the future of radiotheranostics, emphasizing emerging technologies and promising research directions.

The second volume of this book takes a more advanced approach, delving into dosimetric and radiation safety considerations. It aims to empower medical physicists and provide valuable guidance to the cancer community on how to improve cancer control and enhance patient survival times. The book covers topics such as radiation dose calculation, radiation protection principles, and radiation safety management.

With its rigorous approach and comprehensive coverage, this two-volume book is an invaluable resource for medical and health physicists with a basic knowledge of nuclear medicine. It serves as a comprehensive reference for practitioners, researchers, and students interested in advancing the field of radiotheranostics in cancer control.

Weight: 590g
Dimension: 254 x 178 (mm)
ISBN-13: 9781032138978