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Regulatory T cells and Autoimmune Diseases
Regulatory T cells and Autoimmune Diseases
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Recent findings on the role of Tregs in the pathogenesis of autoimmune diseases and their therapeutic applications are discussed in Regulatory T Cells and Autoimmune Diseases. It focuses on Treg-based therapeutics and their targets to manage various autoimmune diseases, including rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood, blood vessel, and eye diseases. The book also covers vaccine-induced effects on Tregs and the development of CAR Treg therapy. It is a valuable resource for researchers and clinicians interested in understanding and developing treatments for autoimmune diseases.
Format: Paperback / softback
Length: 982 pages
Publication date: 24 May 2024
Publisher: Elsevier Science Publishing Co Inc
The role of regulatory T cells (Tregs) in the pathogenesis of autoimmune diseases has been a subject of intense research in recent years. In this comprehensive book, Regulatory T Cells and Autoimmune Diseases delves into the latest findings regarding the contribution of Tregs to the development of these diseases and explores their therapeutic potential.
Chapter 1 provides an overview of the role of Tregs in immune regulation and their involvement in autoimmune diseases. It discusses the different types of Tregs and their functions, as well as the mechanisms by which they suppress immune responses.
Chapter 2 explores the mechanisms by which Tregs can contribute to autoimmune disease development. It discusses the role of Treg-mediated immune suppression, the influence of environmental factors, and the role of genetic predisposition in the development of autoimmune diseases.
Chapter 3 focuses on the therapeutic applications of Tregs. It discusses the use of Treg-based therapies for autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, and psoriasis. It also covers the development of CAR Treg therapy, a promising approach for treating autoimmune diseases.
Chapter 4 examines the vaccine-induced effects on the functioning of Tregs and the development of CAR Treg therapy for autoimmune diseases. It discusses the potential benefits and challenges of CAR Treg therapy and highlights the need for further research in this area.
Chapter 5 concludes with a discussion of current challenges and future prospects of Treg-based therapeutics. It explores the potential for personalized medicine approaches, the development of new Treg-based therapies, and the need for better understanding of the mechanisms underlying Treg-mediated immune suppression.
Regulatory T Cells and Autoimmune Diseases is an essential resource for both basic and advanced researchers in the field of immunology and autoimmune diseases. It provides a comprehensive and up-to-date overview of the role of Tregs in autoimmune disease pathogenesis and therapy, and offers valuable insights into the potential for developing new and effective treatments for these diseases.
Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780443139475
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