Sarcoplasmic Reticulum in Muscle Physiology: 2 volume set

This 2-volume set, first published in 1986, explores the role of the sarcoplasmic reticulum in muscle physiology, serving as a valuable reference for myology students with extensive notes, diagrams, and references.

Format: Hardback
Length: 456 pages
Publication date: 30 December 2021
Publisher: Taylor & Francis Ltd

First published in 1986, this two-volume set delves into the intricate role of the sarcoplasmic reticulum in the cellular physiology of muscle structures. Extensively compiled and meticulously annotated with an abundance of notes, diagrams, and references, this comprehensive volume set serves as an invaluable resource for students of myology.

The sarcoplasmic reticulum (SR) is a crucial component of muscle cells, responsible for numerous essential functions. It plays a pivotal role in muscle contraction by facilitating the release of calcium ions from the internal calcium store, which triggers the contraction of muscle fibers. Additionally, the SR is involved in muscle relaxation by reuptaking calcium ions and returning them to the internal store, which leads to muscle relaxation.

The SR is a highly organized structure composed of two main parts: the SR membrane and the SR lumen. The SR membrane is a thin, flexible membrane that surrounds the SR lumen and is responsible for regulating the flow of calcium ions. The SR lumen is a spacious compartment that contains a high concentration of calcium ions and other molecules that are essential for muscle function.

One of the key functions of the SR is to regulate the concentration of calcium ions in muscle cells. This is achieved through a series of mechanisms, including the release of calcium ions from the internal calcium store through the action of calcium channels, the reuptake of calcium ions by the SR through the action of calcium pumps, and the recycling of calcium ions back to the internal calcium store through the action of calcium exchangers.

The SR also plays a role in the storage and transport of other molecules that are essential for muscle function. These molecules include ATP, which is the primary energy source for muscle contraction, and myosin, which is the protein responsible for muscle contraction. The SR can store large amounts of ATP and myosin, allowing muscle cells to maintain their energy levels and contract for extended periods of time.

In addition to its role in muscle function, the SR is also involved in several other cellular processes, including cell signaling, apoptosis, and the regulation of gene expression. The SR has been shown to interact with a variety of signaling pathways, including the calcium-calmodulin signaling pathway and the protein kinase C signaling pathway, which are involved in muscle contraction and relaxation.

The SR is a complex structure that plays a critical role in the cellular physiology of muscle structures. Its regulation of calcium ions and other molecules is essential for muscle contraction and relaxation, and its involvement in other cellular processes is important for maintaining muscle health and function.

In conclusion, the sarcoplasmic reticulum is a vital component of muscle cells that plays a critical role in muscle contraction and relaxation. Its regulation of calcium ions and other molecules is essential for muscle function, and its involvement in other cellular processes is important for maintaining muscle health and function.

Dimension: 254 x 178 (mm)
ISBN-13: 9780367276980