Single Biomolecule Detection and Analysis: Concepts, Applications, and Future Prospects

This collection discusses various micro/nanodevice design and fabrication for single-biomolecules detection, covering electrochemical, optical, and nanopore devices. It is a valuable resource for graduate students and professionals in materials science, biomedical engineering, chemical engineering, mechanical engineering, and nanoscience.

Format: Hardback
Length: 338 pages
Publication date: 15 August 2023
Publisher: Taylor & Francis Ltd

This comprehensive collection delves into the intricate design and fabrication of micro/nanodevices for the precise detection of single biomolecules. Serving as an invaluable reference text for both graduate students and seasoned professionals across a wide range of disciplines, including materials science, biomedical engineering, chemical engineering, mechanical engineering, and nanoscience, it offers a deep understanding of the latest advancements in this field.

The book begins by exploring the techniques employed for single-biomolecule detection, highlighting their advantages, limitations, and diverse applications. It provides a comprehensive overview of various electrochemical detection methods, offering a detailed account of their principles, mechanisms, and practical implementations. Furthermore, the book delves into the intricate processes of single-molecule separation, sensing, imaging, sequencing, and analysis, providing a thorough exploration of the methodologies and tools employed in these domains.

In addition to covering conventional detection techniques, the book also examines the emerging field of cantilever-based biomolecule sensing, shedding light on its potential and limitations. It explores different types of cantilever-based sensors, including their design, fabrication, and applications in various fields. The text further examines single-molecule optical and nanopore devices, highlighting their unique advantages and challenges in detecting and analyzing biomolecules.

Single Biomolecule Detection and Analysis encompasses a wide range of biosensors-based detection methods, including stochastic optical reconstruction microscopy-based detection, electrochemical detection, metabolic engineering of animal cells, single-molecule intracellular delivery and tracking, terahertz spectroscopy-based detection, total internal reflection fluorescence (TIFR) detection, and Fluorescence Correlation Spectroscopy (FCS) detection. Each chapter provides a detailed explanation of the underlying principles, experimental setups, and applications of these detection techniques, making it an essential resource for researchers and practitioners in the field.

With its extensive coverage, comprehensive insights, and practical applications, this book serves as a valuable resource for graduate students and professionals seeking to advance their knowledge and expertise in single-biomolecule detection and analysis. It equips readers with the necessary tools and knowledge to contribute to the development of innovative technologies and applications in this rapidly evolving field.

Dimension: 234 x 156 (mm)
ISBN-13: 9780367754303