Shulph Ink
Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease
Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease
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Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease explores the role of sirtuins in the body during normal physiology and disease, emphasizing their potential for developing therapeutic strategies for various disorders. These histone deacetylases play a crucial role in cellular survival, longevity, and the pathology of diseases such as neurodegenerative, cardiovascular, immune, reproductive, endocrine, gastrointestinal, drug dependency, and aging-related disorders. The book presents novel signaling pathways for sirtuins that promote stem cell proliferation, cellular protection, apoptosis and autophagy, and lifespan extension, making it a valuable resource for scientists, physicians, pharmaceutical industry experts, nutritionists, and students.
Format: Paperback / softback
Length: 420 pages
Publication date: 25 February 2021
Publisher: Elsevier Science Publishing Co Inc
Sirtuins, the fascinating proteins that play a crucial role in regulating various biological processes within our bodies, have emerged as a promising target for developing innovative therapeutic strategies in medicine. This comprehensive book, Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease, delves deep into the role of sirtuins during normal physiology as well as in disease conditions, emphasizing the potential of targeting sirtuin-controlled pathways to develop effective treatments for a wide range of disorders.
Sirtuins, which are expressed throughout the body, have broad biological effects and can significantly impact cellular survival and longevity during acute and long-term illnesses. These histone deacetylases play an intricate role in the pathology, progression, and treatment of several disease entities, including neurodegenerative disorders, cardiovascular disease, immune system dysfunction, reproductive dysfunction, endocrine disorders, gastrointestinal disease, drug dependency, and aging-related disorders.
Implementing a translational medicine format, this unique reference highlights novel signaling pathways for sirtuins that promote stem cell proliferation, enhance cellular protection, modulate pathways of apoptosis and autophagy, and extend lifespan. Each chapter is presented with insightful detail that will be of interest and a comprehensive resource to audiences that include scientists, physicians, pharmaceutical industry experts, nutritionists, and students.
In conclusion, Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease provides a valuable insight into the role of sirtuins in health and disease. By exploring the targeting of sirtuin-controlled pathways for therapeutic development, this book offers a promising avenue for improving the treatment of a wide range of disorders and enhancing human longevity.
Weight: 1152g
Dimension: 216 x 278 x 35 (mm)
ISBN-13: 9780128141182
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