Site-specific Cancer Nanotheranostics: A Microenvironment-responsive Approach

This book covers recent progress in developing tumor-responsive and site-specific delivery platforms and explores characterization techniques and toxicological and regulatory aspects. It is a timely volume as global research in oncology moves towards biochemical signal-based and cell environment-inspired therapeutic strategies.

Format: Hardback
Length: 368 pages
Publication date: 19 October 2023
Publisher: Taylor & Francis Ltd

This comprehensive book delves into the latest advancements in the development of tumor-responsive and site-specific delivery platforms, along with a wide range of associated chemistries. It emerges as a timely publication, aligning with the growing trend in global oncology toward biochemical signal-based and cell environment-inspired therapeutic approaches. Furthermore, the book underscores the importance of exploring various characterization techniques for stimuli-responsive nanoplatforms and addressing toxicological and regulatory considerations.

The book offers a focused and comprehensive perspective on theranostics in cancer intervention, encompassing not only the multifunctionality of nanosystems but also providing a thorough overview of niche technical aspects. Its content is designed to cater to both early-career and experienced readers, offering valuable strategies from esteemed authorities in the field on a global scale.

Chapter 1: Introduction
This chapter provides an overview of the book's scope and highlights the significance of tumor-responsive and site-specific delivery platforms in cancer therapy. It discusses the challenges faced in conventional drug delivery systems and the need for innovative approaches to improve therapeutic efficacy.

Chapter 2: Nanoparticle Platforms for Cancer Therapy
Chapter 2 explores the use of nanoparticles as drug delivery vehicles for cancer therapy. It discusses the synthesis, characterization, and modification of nanoparticles to enhance their tumor targeting properties and improve drug payload delivery. The chapter also covers various nanoparticle-based drug delivery systems, such as liposomes, polymeric nanoparticles, and nanocarriers, and their applications in cancer treatment.

Chapter 3: Targeted Drug Delivery Systems
Chapter 3 focuses on targeted drug delivery systems that utilize molecularly targeted agents to enhance the therapeutic effect of drugs. It discusses the development of targeted drug delivery platforms, including antibody-drug conjugates, small interfering RNAs (siRNAs), and gene therapy vectors. The chapter also explores the mechanisms of targeted drug delivery and the challenges associated with its implementation.

Chapter 4: Chemistries for Tumor-Responsive and Site-Specific Delivery Platforms
Chapter 4 discusses the range of chemistries used in tumor-responsive and site-specific delivery platforms. It covers drug conjugates, polymers, biomaterials, and nanomaterials, and their applications in cancer therapy. The chapter also highlights the importance of chemistries in controlling drug release, improving stability, and enhancing tumor targeting.

Chapter 5: Characterization Techniques for Stimuli-Responsive Nanoplatforms
Chapter 5 explores the use of various characterization techniques to evaluate the stimuli-responsive behavior of nanoplatforms. It discusses the techniques used to measure drug release, cellular uptake, and cellular response to nanoplatforms. The chapter also highlights the importance of characterization in understanding the toxicological and regulatory aspects of nanoplatforms.

Chapter 6: Toxicological and Regulatory Aspects of Nanoplatforms
Chapter 6 addresses the toxicological and regulatory aspects of nanoplatforms. It discusses the safety concerns associated with the use of nanomaterials in cancer therapy and the regulatory frameworks in place to ensure their safe and effective use. The chapter also provides insights into the future directions in toxicological and regulatory research in the field of nanomedicine.

Chapter 7: Conclusion
Chapter 7 summarizes the key findings and conclusions of the book. It highlights the importance of interdisciplinary research and collaboration in developing effective tumor-responsive and site-specific delivery platforms. The chapter also provides recommendations for future research and development in the field of nanomedicine.

In conclusion, this comprehensive book provides a valuable resource for researchers, clinicians, and students interested in the development of tumor-responsive and site-specific delivery platforms and associated chemistries. It offers a different angle on theranostics in cancer intervention, targeting not only the multifunctionality of nanosystems but also providing a comprehensive overview of niche technical aspects. By emphasizing the need to explore various characterization techniques for specific stimuli-responsive nanoplatforms and addressing toxicological and regulatory considerations, the book contributes to the advancement of nanomedicine and the development of more effective cancer therapies.

Weight: 880g
Dimension: 254 x 178 (mm)
ISBN-13: 9781032434827