Stem Cell Production: Processes, Practices and Regulations

This book explores the technologies and processes for developing and commercializing stem cells according to cGMP guidelines, discussing their therapeutic potentials and recent developments in bioreactor cultivation. It also introduces techniques for characterizing stem cells and optimizing cell transporting conditions.

Format: Paperback / softback
Length: 272 pages
Publication date: 31 March 2023
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the intricate technologies and processes involved in the development and commercial production of stem cells, adhering to stringent cGMP guidelines. The introductory chapter explores the remarkable therapeutic potential of stem cells in treating a wide range of diseases, including degenerative disorders and genetic diseases. It then provides a detailed review of the recent advancements in the cultivation of stem cells within bioreactors, encompassing critical cultural parameters, potential bioreactor configurations, and innovative technologies integrated into the bioprocess developmental stages.

Furthermore, the book introduces microscopic, molecular, and cellular techniques for the characterization of stem cells, essential for obtaining regulatory approvals. It also outlines optimal cell transporting conditions to ensure cell viability and maintain their properties. Additionally, the book summarizes characterization strategies for clinical-grade stem cells, emphasizing their importance in stem cell therapy.

As a valuable resource for both academic and industrial stakeholders, this book offers a deep understanding of R&D and manufacturing of clinical-grade stem cells, paving the way for groundbreaking advancements in medical research and therapeutic applications.

Weight: 438g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811675911
Edition number: 1st ed. 2022