Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects and Asymmetric Synthesis

Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects, and Asymmetric Synthesis is a comprehensive textbook that covers the stereochemistry of reactions, including ionic, pericyclic, transition metal-catalyzed, radical, and photochemical reactions. It includes chapters on acyclic molecules, cyclic molecules, the stereochemistry of organic reactions, the perturbation molecular orbital theory, and stereoselectivity and hierarchical levels of asymmetric synthesis. Each chapter includes problems to reinforce the main themes, making it valuable for students, teachers, and researchers in organic, biological, and medicinal chemistry, as well as biologists, pharmacologists, polymer chemists, and chemists.

Format: Paperback / softback
Length: 638 pages
Publication date: 23 April 2021
Publisher: Elsevier Science Publishing Co Inc

Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects, and Asymmetric Synthesis is a comprehensive textbook that delves into the intricate world of stereochemistry and organic reactions. Spanning a wide range of mechanistic types, from ionic, pericyclic, and transition metal-catalyzed reactions to radical and photochemical processes, this text offers a comprehensive exploration of the stereochemistry of these reactions.

The book is organized into several chapters, each dedicated to a specific aspect of stereochemistry and organic reactions. The first chapter provides an introduction to acyclic molecules, their structures, and the principles governing their stereochemistry. It also introduces the concept of chirality, which plays a crucial role in understanding the stereochemistry of organic compounds.

The second chapter focuses on cyclic molecules and their stereochemistry. It discusses the conformational analysis of cyclic compounds, including the use of molecular modeling techniques to predict their stereochemistry. The chapter also explores the stereoelectronic effects in cyclic molecules, which are influenced by the presence of pi-conjugated systems and the cyclic structure itself.

The third chapter delves into the stereochemistry of organic reactions. It discusses the factors that influence the stereoselectivity of reactions, such as the nature of the reactants, the presence of chiral centers, and the influence of transition states. The chapter also introduces the perturbation molecular orbital theory, which explains the origin of stereoelectronic effects.

The fourth chapter provides an introduction to the principles of stereoselectivity and hierarchical levels of asymmetric synthesis. It discusses the strategies used to achieve selective synthesis of complex organic molecules, including the use of chiral catalysts, organocatalysis, and asymmetric synthesis techniques.

Each chapter includes a comprehensive set of problems that reinforce the main themes of the text. These problems are designed to assist students, teachers, and researchers in organic, biological, and medicinal chemistry, as well as biologists, pharmacologists, polymer chemists, and chemists. The problems cover a wide range of topics, from basic stereochemistry to advanced organic reactions and asymmetric synthesis.

Stereochemistry and Organic Reactions: Conformation, Configuration, Stereoelectronic Effects, and Asymmetric Synthesis is an essential textbook for anyone interested in the field of stereochemistry and organic reactions. It provides a comprehensive and up-to-date coverage of the subject, making it valuable to students, teachers, and researchers alike. With its clear and concise writing style, extensive problem sets, and comprehensive coverage of key topics, this text is an invaluable resource for anyone seeking to deepen their understanding of stereochemistry and organic reactions.

Weight: 1034g
Dimension: 153 x 229 x 38 (mm)
ISBN-13: 9780128240922