Successes and Challenges of NK Immunotherapy: Breaking Tolerance to Cancer Resistance

NK Immunotherapy: Increasing Anti-tumor Efficacy discusses the unique therapeutic applications of NK cells to fight cancers and eliminate cancer stem cells, providing information on their development, engineering, mechanisms of action, and clinical trials.

Format: Hardback
Length: 538 pages
Publication date: 25 June 2021
Publisher: Elsevier Science Publishing Co Inc

NK Immunotherapy: Increasing Anti-tumor Efficacy delves into the remarkable therapeutic potential of NK cells in combating cancers and eradicating the majority and subset of cancer stem cells responsible for metastasis, relapse, and recurrences. This comprehensive book offers valuable insights into the development, engineering, mechanisms of action, response to various preclinical models, and applications in diverse clinical trials. It encompasses various sections, including the creation of highly engineered cytotoxic NK cells, their operational mechanisms, preclinical and clinical applications, the development and utilization of CAR-NK cells, and the exploration of novel NK-drug conjugates. Furthermore, it emphasizes the ability of activated NK cells to target and eliminate highly resistant cancer stem cells. Authored by esteemed experts in NK immunotherapy across the globe, this publication serves as a crucial resource for researchers, clinicians, and individuals engaged in the field of biomedical research, seeking to understand innovative and effective therapies for cancer treatment.

Weight: 1248g
Dimension: 240 x 244 x 31 (mm)
ISBN-13: 9780128243756